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cbc1 nuclear cap-binding complex large subunit [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542556, updated on 18-Sep-2024

Summary

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Official Symbol
cbc1
Official Full Name
nuclear cap-binding complex large subunit
Primary source
PomBase:SPAC6G10.07
Locus tag
SPOM_SPAC6G10.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See cbc1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (3228510..3231398)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene TRAPP complex subunit Trs120 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene FAD-dependent amino acid oxidase Neighboring gene ncRNA Neighboring gene isocitrate dehydrogenase Idp1 Neighboring gene uncharacterized protein Neighboring gene glucosidase I Gls1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Clr4 specificity and catalytic activity beyond H3K9 methylation. Kusevic D, et al. Biochimie, 2017 Apr. PMID 28143796
  2. Conserved protein Pir2(ARS2) mediates gene repression through cryptic introns in lncRNAs. Thillainadesan G, et al. Nat Commun, 2020 May 15. PMID 32415063, Free PMC Article
  3. Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis. Pebernard S, et al. Mol Biol Cell, 2004 Nov. PMID 15331764, Free PMC Article
  4. The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome. Zhou Y, et al. Nat Commun, 2015 May 20. PMID 25989903, Free PMC Article
  5. Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs. Lemieux C, et al. Nucleic Acids Res, 2009 Jun. PMID 19336419, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA 7-methylguanosine cap binding IC
Inferred by Curator
more info
  
enables RNA cap binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nuclear polyadenylation-dependent CUT catabolic process IC
Inferred by Curator
more info
  
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
part_of nuclear cap binding complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
nuclear cap-binding complex large subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3228510..3231398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019528.3 → NP_594104.1  nuclear cap-binding complex large subunit [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594104.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14253
    Conserved Domains (3) summary
    pfam02854
    Location:36 → 249
    MIF4G; MIF4G domain
    pfam09088
    Location:309 → 499
    MIF4G_like; MIF4G like
    pfam09090
    Location:517 → 710
    MIF4G_like_2; MIF4G like
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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