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lrs1 leucine--tRNA (Leu) ligase Lrs1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542670, updated on 18-Sep-2024

Summary

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Official Symbol
lrs1
Official Full Name
leucine--tRNA (Leu) ligase Lrs1
Primary source
PomBase:SPAC26F1.13c
Locus tag
SPOM_SPAC26F1.13C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See lrs1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5148833..5152492)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene flavoprotein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein hgh1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. tRNA production links nutrient conditions to the onset of sexual differentiation through the TORC1 pathway. Otsubo Y, et al. EMBO Rep, 2018 Mar. PMID 29330317, Free PMC Article
  2. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article
  3. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
  4. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables aminoacyl-tRNA editing activity IEA
Inferred from Electronic Annotation
more info
  
enables leucine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
  
involved_in leucyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
leucine--tRNA (Leu) ligase Lrs1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5148833..5152492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020311.3 → NP_594882.1  leucine--tRNA (Leu) ligase Lrs1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594882.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10490
    Conserved Domains (4) summary
    cd07959
    Location:776 → 895
    Anticodon_Ia_Leu_AEc; Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases
    cd00812
    Location:549 → 778
    LeuRS_core; catalytic core domain of leucyl-tRNA synthetases
    PLN02959
    Location:21 → 1106
    PLN02959; aminoacyl-tRNA ligase
    cl00015
    Location:66 → 225
    nt_trans; nucleotidyl transferase superfamily
Nucleotide Protein
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