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erg12 mevalonate kinase Erg12 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542818, updated on 18-Sep-2024

Summary

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Official Symbol
erg12
Official Full Name
mevalonate kinase Erg12
Primary source
PomBase:SPAC13G6.11c
Locus tag
SPOM_SPAC13G6.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See erg12 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (194099..195634, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene meiotic fizzy-related APC coactivator Fzr2 Neighboring gene SSU-rRNA maturation Tsr4 family protein Neighboring gene O-glucosyl hydrolase Asl1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene chitin synthase I Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast. Fang Y, et al. Genes Cells, 2009 Jun. PMID 19486165
  2. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
  3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables magnesium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables mevalonate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ergosterol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IC
Inferred by Curator
more info
  
involved_in isopentenyl diphosphate biosynthetic process, mevalonate pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
mevalonate kinase Erg12

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    194099..195634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018238.3 → NP_592837.1  mevalonate kinase Erg12 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592837.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09780
    Conserved Domains (3) summary
    COG1577
    Location:5 → 365
    ERG12; Mevalonate kinase [Lipid transport and metabolism]
    pfam00288
    Location:125 → 203
    GHMP_kinases_N; GHMP kinases N terminal domain
    pfam08544
    Location:282 → 341
    GHMP_kinases_C; GHMP kinases C terminal
Nucleotide Protein
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