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lys2 homoaconitate hydratase Lys2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542867, updated on 10-Oct-2024

Summary

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Official Symbol
lys2
Official Full Name
homoaconitate hydratase Lys2
Primary source
PomBase:SPAC343.16
Locus tag
SPOM_SPAC343.16
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See lys2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1675802..1678118)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene translation initiation factor eIF2B beta subunit Neighboring gene WD repeat-containing protein Neighboring gene tRNA isopentenyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SUMO-targeted ubiquitin-protein ligase subunit Rfp2 Neighboring gene 1-phosphatidylinositol 4-kinase Lsb6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nuclear aconitase antagonizes heterochromatic silencing by interfering with Chp1 binding to DNA. Jung SJ, et al. Biochem Biophys Res Commun, 2019 Aug 27. PMID 31255284
  2. Cloning the Schizosaccharomyces pombe lys2+ gene and construction of new molecular genetic tools. Hoffman RL, et al. Curr Genet, 2006 Jun. PMID 16491385, Free PMC Article
  3. Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe. Ye ZH, et al. J Bacteriol, 1988 Dec. PMID 3142867, Free PMC Article
  4. Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast. Ma Y, et al. Curr Genet, 2007 Aug. PMID 17622533
  5. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Aco2 antagonizes heterochromatic silencing by interfering with Chp1 binding to DNA.
    Title: Nuclear aconitase antagonizes heterochromatic silencing by interfering with Chp1 binding to DNA.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables homoaconitate hydratase activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
Process Evidence Code Pubs
involved_in lysine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in lysine biosynthetic process via aminoadipic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial matrix IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
homoaconitate hydratase Lys2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1675802..1678118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018870.3 → NP_593437.2  homoaconitate hydratase Lys2 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN2H7T3
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials