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btb3 ubiquitin ligase Btb3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542872, updated on 18-Sep-2024

Summary

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Official Symbol
btb3
Official Full Name
ubiquitin ligase Btb3
Primary source
PomBase:SPAC13D6.04c
Locus tag
SPOM_SPAC13D6.04C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See btb3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (2251442..2253352, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA (uridine) methyltransferase trm9 Neighboring gene ncRNA Neighboring gene tubulin-specific chaperone cofactor B Neighboring gene ncRNA Neighboring gene ribonuclease H2 complex subunit Rnh201

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase. Maezawa S, et al. Genes Cells, 2008 May. PMID 18429817
  2. BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Geyer R, et al. Mol Cell, 2003 Sep. PMID 14527422
  3. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
  4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ubiquitin ligase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin ligase Btb3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2251442..2253352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019114.3 → NP_593682.1  ubiquitin ligase Btb3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593682.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10225
    Conserved Domains (5) summary
    smart00225
    Location:168 → 262
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cd00204
    Location:56 → 139
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00651
    Location:164 → 256
    BTB; BTB/POZ domain
    pfam12796
    Location:56 → 140
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:56 → 83
    ANK; ANK repeat [structural motif]
Nucleotide Protein
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