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abp1 cofilin/tropomyosin family protein abp1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542979, updated on 18-Sep-2024

Summary

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Official Symbol
abp1
Official Full Name
cofilin/tropomyosin family protein abp1
Primary source
PomBase:SPAPJ760.02c
Locus tag
SPOM_SPAPJ760.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See abp1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (5261935..5265046, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F1-FO ATP synthase alpha subunit Neighboring gene dipeptidyl peptidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein adg1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The fission yeast CENP-B protein Abp1 prevents pervasive transcription of repetitive DNA elements. Daulny A, et al. Biochim Biophys Acta, 2016 Oct. PMID 27345571, Free PMC Article
  2. Structure of the replication regulator Sap1 reveals functionally important interfaces. Jørgensen MM, et al. Sci Rep, 2018 Jul 19. PMID 30026545, Free PMC Article
  3. Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization. Murton HE, et al. Genetics, 2016 Aug. PMID 27343236, Free PMC Article
  4. Role of actin polymerization and actin cables in actin-patch movement in Schizosaccharomyces pombe. Pelham RJ Jr, et al. Nat Cell Biol, 2001 Mar. PMID 11231572
  5. A stable microtubule array drives fission yeast polarity reestablishment upon quiescence exit. Laporte D, et al. J Cell Biol, 2015 Jul 6. PMID 26124291, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results suggest that Abp1 prevents pervasive RNAPII transcription of repetitive DNA elements (ie, Tf2 and rDNA repeats) from internal cryptic sites.
    Title: The fission yeast CENP-B protein Abp1 prevents pervasive transcription of repetitive DNA elements.
  2. we describe the impact of silencing and clustering on the mobility of an endogenous Tf2 element. Deletion of genes such as set1(+) or abp1(+) that both alleviate silencing and clustering, result in a corresponding increase in mobilization. Furthermore, expression of constitutively active Sre1, a transcriptional activator of Tf2 elements, also alleviates clustering and induces mobilization
    Title: Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of actin filament polymerization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actin body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in actin cortical patch IDA
Inferred from Direct Assay
more info
 PubMed 
colocalizes_with actin filament IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cell division site HDA PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cortical actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in site of polarized growth IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cofilin/tropomyosin family protein abp1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5261935..5265046 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020353.3 → NP_594921.1  cofilin/tropomyosin family protein abp1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594921.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P78815, Q9P7E8
    Conserved Domains (3) summary
    cd11281
    Location:5 → 138
    ADF_drebrin_like; ADF homology domain of drebrin and actin-binding protein 1 (abp1)
    cd11961
    Location:804 → 856
    SH3_Abp1_fungi_C2; Second C-terminal Src homology 3 domain of Fungal Actin-binding protein 1
    cl17036
    Location:729 → 782
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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