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psm3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543010, updated on 11-Sep-2024

Summary

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Official Symbol
psm3
Primary source
PomBase:SPAC10F6.09c
Locus tag
SPOM_SPAC10F6.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
smc3
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Genomic context

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Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (1220969..1224858, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein mug94 Neighboring gene ncRNA Neighboring gene Ino80 complex HMG box subunit Nht1 Neighboring gene RIO family protein kinase Neighboring gene autophagy-associated protein kinase activator Atg17 Neighboring gene ncRNA Neighboring gene protein-S isoprenylcysteine O-methyltransferase Mam4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast. Folco HD, et al. Curr Biol, 2015 Feb 2. PMID 25619765, Free PMC Article
  2. Psm3 acetylation on conserved lysine residues is dispensable for viability in fission yeast but contributes to Eso1-mediated sister chromatid cohesion by antagonizing Wpl1. Feytout A, et al. Mol Cell Biol, 2011 Apr. PMID 21300781, Free PMC Article
  3. DNA Binding by the Mis4(Scc2) Loader Promotes Topological DNA Entrapment by the Cohesin Ring. Kurokawa Y, et al. Cell Rep, 2020 Nov 10. PMID 33176147
  4. Acetylation regulates monopolar attachment at multiple levels during meiosis I in fission yeast. Kagami A, et al. EMBO Rep, 2011 Oct 28. PMID 21979813, Free PMC Article
  5. Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein-protein assembly. Sakai A, et al. EMBO J, 2003 Jun 2. PMID 12773391, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Psm3 acetylation contributes to Eso1 counteracting of Wpl1 to secure stable cohesin interaction with postreplicative chromosomes
    Title: Psm3 acetylation on conserved lysine residues is dispensable for viability in fission yeast but contributes to Eso1-mediated sister chromatid cohesion by antagonizing Wpl1.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
contributes_to double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to topological DNA co-entrapment activity EXP
Inferred from Experiment
more info
 PubMed 
contributes_to topological DNA co-entrapment activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin looping IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in homologous chromosome orientation in meiotic metaphase I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic sister chromatid cohesion EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitotic sister chromatid cohesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic sister chromatid cohesion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitotic sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in condensed chromosome, centromeric region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
part_of meiotic cohesin complex NAS
Non-traceable Author Statement
more info
  
part_of mitotic cohesin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitotic cohesin complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
mitotic/meiotic cohesin complex ATPase subunit Psm3/Smc3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1220969..1224858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018657.3 → NP_593260.1  mitotic/meiotic cohesin complex ATPase subunit Psm3/Smc3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593260.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42649
    Conserved Domains (1) summary
    COG1196
    Location:1 → 1192
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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