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tif308 translation initiation factor eIF3h (p40) [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543153, updated on 18-Sep-2024

Summary

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Official Symbol
tif308
Official Full Name
translation initiation factor eIF3h (p40)
Primary source
PomBase:SPAC821.05
Locus tag
SPOM_SPAC821.05
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
eif8; tif38
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Genomic context

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See tif308 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (988361..989866)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene cytoplasmic poly(A) polymerase Cid13 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitotic and meiotic (sporulation) septin Spn2 Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor Moc3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes. Zhou C, et al. BMC Biol, 2005 May 17. PMID 15904532, Free PMC Article
  2. Fission yeast translation initiation factor 3 subunit eIF3h is not essential for global translation initiation, but deletion of eif3h+ affects spore formation. Ray A, et al. Yeast, 2008 Nov. PMID 19061185
  3. The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2. Jongjitwimol J, et al. PLoS One, 2014. PMID 24818994, Free PMC Article
  4. Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site. Roberts-Galbraith RH, et al. Mol Cell, 2010 Jul 9. PMID 20603077, Free PMC Article
  5. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. eIF3h deletion mutants are hypersensitive to caffeine and highly defective in meiosis, producing either no spores or incomplete tetrads with a very high frequency.
    Title: Fission yeast translation initiation factor 3 subunit eIF3h is not essential for global translation initiation, but deletion of eif3h+ affects spore formation.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables deubiquitinase activity ISM
Inferred from Sequence Model
more info
  
enables metallopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in formation of cytoplasmic translation initiation complex IEA
Inferred from Electronic Annotation
more info
  
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of COP9 signalosome ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytosol HDA PubMed 
part_of eukaryotic 43S preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic 43S preinitiation complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic 48S preinitiation complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation initiation factor 3 complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
translation initiation factor eIF3h (p40)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    988361..989866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018556.3 → NP_593158.1  translation initiation factor eIF3h (p40) [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593158.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UT48
    Conserved Domains (1) summary
    cd08065
    Location:18 → 308
    MPN_eIF3h; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in eIF2h
Nucleotide Protein
Heading Accession and Version

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