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cuf1 Cu-sensing transcription factor Cuf1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543198, updated on 18-Sep-2024

Summary

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Official Symbol
cuf1
Official Full Name
Cu-sensing transcription factor Cuf1
Primary source
PomBase:SPAC31A2.11c
Locus tag
SPOM_SPAC31A2.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See cuf1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (407714..409845, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene Ran GTPase binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Copper induces cytoplasmic retention of fission yeast transcription factor cuf1. Beaudoin J, et al. Eukaryot Cell, 2006 Feb. PMID 16467469, Free PMC Article
  2. Crm1-mediated nuclear export of the Schizosaccharomyces pombe transcription factor Cuf1 during a shift from low to high copper concentrations. Beaudoin J, et al. Eukaryot Cell, 2007 May. PMID 17384198, Free PMC Article
  3. The Schizosaccharomyces pombe Cuf1 is composed of functional modules from two distinct classes of copper metalloregulatory transcription factors. Beaudoin J, et al. J Biol Chem, 2003 Apr 18. PMID 12578838
  4. Ctr6, a vacuolar membrane copper transporter in Schizosaccharomyces pombe. Bellemare DR, et al. J Biol Chem, 2002 Nov 29. PMID 12244050
  5. Identification of a novel high affinity copper transport complex in the fission yeast Schizosaccharomyces pombe. Zhou H, et al. J Biol Chem, 2001 Jun 8. PMID 11274192

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables copper ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables copper ion binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in copper ion homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular copper ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular copper ion homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular iron ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular iron ion homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Cu-sensing transcription factor Cuf1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    407714..409845 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018324.3 → NP_592923.1  Cu-sensing transcription factor Cuf1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592923.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09728
    Conserved Domains (1) summary
    smart00412
    Location:2 → 40
    Cu_FIST; Copper-Fist
Nucleotide Protein
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