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itt1 ubiquitin-protein ligase E3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543264, updated on 18-Sep-2024

Summary

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Official Symbol
itt1
Official Full Name
ubiquitin-protein ligase E3
Primary source
PomBase:SPAC1002.14
Locus tag
SPOM_SPAC1002.14
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See itt1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1824583..1826248)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene beta-glucosidase Psu1 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene mediator complex subunit Med6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nicotinic acid plasma membrane transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  3. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
  4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
  5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in regulation of cytoplasmic translational termination ISO
Inferred from Sequence Orthology
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquitin-protein ligase E3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1824583..1826248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018936.3 → NP_593502.1  ubiquitin-protein ligase E3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593502.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9US46
    Conserved Domains (4) summary
    smart00591
    Location:17 → 134
    RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain
    smart00647
    Location:246 → 306
    IBR; In Between Ring fingers
    pfam01485
    Location:367 → 398
    IBR; IBR domain, a half RING-finger domain
    pfam14634
    Location:174 → 201
    zf-RING_5; zinc-RING finger domain
Nucleotide Protein
Heading Accession and Version

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