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mtf1 RNA polymerase-specificity factor Mtf1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543271, updated on 18-Sep-2024

Summary

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Official Symbol
mtf1
Official Full Name
RNA polymerase-specificity factor Mtf1
Primary source
PomBase:SPAC1002.08c
Locus tag
SPOM_SPAC1002.08C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mtf1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1809480..1811330, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene N-acetyltransferase Ats1 Neighboring gene ncRNA Neighboring gene bouquet formation protein Bqt2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dihydrolipoamide dehydrogenase Dld1 Neighboring gene ncRNA Neighboring gene snRNP binding protein Sgt1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe. Jiang H, et al. Nucleic Acids Res, 2011 Jul. PMID 21357609, Free PMC Article
  2. A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1. Sun W, et al. Nucleic Acids Res, 2011 Apr. PMID 21138961, Free PMC Article
  3. Targeting mitochondrial transcription in fission yeast with ETB, an inhibitor of HSP60, the chaperone that binds to the mitochondrial transcription factor Mtf1. Sun W, et al. Genes Cells, 2012 Feb. PMID 23035257
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Deletion mutants show Mtf1 to be essential for cell growth, cell morphology and mitochondrial membrane potential.
    Title: Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe.
  2. Over expression of Mtf1 induced transcription of the srk1 gene and Mtf1 deletion led to a reduction in transcription of the srk1 gene in vivo.
    Title: A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables mitochondrial transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA (adenine) methyltransferase activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in mitochondrial transcription EXP
Inferred from Experiment
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation at mitochondrial promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation at mitochondrial promoter IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mitochondrial DNA-directed RNA polymerase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial DNA-directed RNA polymerase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion HDA PubMed 
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
RNA polymerase-specificity factor Mtf1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1809480..1811330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018929.3 → NP_593495.1  RNA polymerase-specificity factor Mtf1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593495.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9US51
    Conserved Domains (1) summary
    pfam00398
    Location:26 → 350
    RrnaAD; Ribosomal RNA adenine dimethylase
Nucleotide Protein
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Gene LinkOut

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