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cbh1 CENP-B protein 1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543290, updated on 18-Sep-2024

Summary

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Official Symbol
cbh1
Official Full Name
CENP-B protein 1
Primary source
PomBase:SPAC9E9.10c
Locus tag
SPOM_SPAC9E9.10C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
cbh
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Genomic context

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See cbh1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4458920..4460878, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pyridoxal reductase Plr1 Neighboring gene ABC transmembrane transporter Abc1/Ybt1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe. Lee JK, et al. Proc Natl Acad Sci U S A, 1997 Aug 5. PMID 9237993, Free PMC Article
  2. Fission yeast homologs of human CENP-B have redundant functions affecting cell growth and chromosome segregation. Baum M, et al. Mol Cell Biol, 2000 Apr. PMID 10733588, Free PMC Article
  3. CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR. Zaratiegui M, et al. Nature, 2011 Jan 6. PMID 21151105, Free PMC Article
  4. Functional redundancies, distinct localizations and interactions among three fission yeast homologs of centromere protein-B. Irelan JT, et al. Genetics, 2001 Mar. PMID 11238404, Free PMC Article
  5. A homolog of male sex-determining factor SRY cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination. Matsuda E, et al. Proc Natl Acad Sci U S A, 2011 Nov 15. PMID 22042869, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mc, a homolog of male sex-determining factor SRY, cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination
    Title: A homolog of male sex-determining factor SRY cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables centromeric DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in chromatin NAS
Non-traceable Author Statement
more info
  
is_active_in condensed chromosome, centromeric region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
CENP-B protein 1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4458920..4460878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020012.3 → NP_594583.1  CENP-B protein 1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594583.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14294, O14423
    Conserved Domains (3) summary
    smart00674
    Location:76 → 143
    CENPB; Putative DNA-binding domain in centromere protein B, mouse jerky and transposases
    pfam03184
    Location:207 → 384
    DDE_1; DDE superfamily endonuclease
    cl18945
    Location:6 → 103
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
Nucleotide Protein
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