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end4 clathrin adaptor End4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543336, updated on 18-Sep-2024

Summary

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Official Symbol
end4
Official Full Name
clathrin adaptor End4
Primary source
PomBase:SPAC688.11
Locus tag
SPOM_SPAC688.11
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
sla2
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Genomic context

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See end4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3134987..3138666)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial pyrimidine nucleotide transporter Neighboring gene DNA polymerase zeta catalytic subunit Rev3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene TatD DNase family Scn1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe. Castagnetti S, et al. J Cell Sci, 2005 May 1. PMID 15827087
  2. Characterization of end4+, a gene required for endocytosis in Schizosaccharomyces pombe. Iwaki T, et al. Yeast, 2004 Jul 30. PMID 15300681
  3. Actin filament severing by cofilin dismantles actin patches and produces mother filaments for new patches. Chen Q, et al. Curr Biol, 2013 Jul 8. PMID 23727096, Free PMC Article
  4. Schizosaccharomyces pombe protein phosphatase 1 in mitosis, endocytosis and a partnership with Wsh3/Tea4 to control polarised growth. Alvarez-Tabarés I, et al. J Cell Sci, 2007 Oct 15. PMID 17895368
  5. The novel fission yeast protein Pal1p interacts with Hip1-related Sla2p/End4p and is involved in cellular morphogenesis. Ge W, et al. Mol Biol Cell, 2005 Sep. PMID 15975911, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables clathrin adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables clathrin light chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cytoskeletal protein-membrane anchor activity EXP
Inferred from Experiment
more info
 PubMed 
enables phosphatidylinositol-3,4-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-3,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in clathrin coat assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in establishment or maintenance of actin cytoskeleton polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in actin cortical patch IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in actin cortical patch IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell cortex of cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in clathrin-coated vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cortical actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm HDA PubMed 
is_active_in endocytic patch IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in medial cortex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in new growing cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in old growing cell tip IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
clathrin adaptor End4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3134987..3138666
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019493.3 → NP_594069.2  clathrin adaptor End4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594069.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P78916, Q9P6L5
    Conserved Domains (3) summary
    smart00307
    Location:902 → 1100
    ILWEQ; I/LWEQ domain
    pfam07651
    Location:14 → 281
    ANTH; ANTH domain
    pfam13851
    Location:468 → 621
    GAS; Growth-arrest specific micro-tubule binding
Nucleotide Protein
Heading Accession and Version

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