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met26 homocysteine methyltransferase Met26 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543585, updated on 18-Sep-2024

Summary

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Official Symbol
met26
Official Full Name
homocysteine methyltransferase Met26
Primary source
PomBase:SPAC9.09
Locus tag
SPOM_SPAC9.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See met26 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1478398..1481172)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene steroid reductase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene plasma membrane thiamine/proton high affinity transmembrane transporter Thi9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Homocysteine accumulation causes a defect in purine biosynthesis: further characterization of Schizosaccharomyces pombe methionine auxotrophs. Fujita Y, et al. Microbiology (Reading), 2006 Feb. PMID 16436428
  2. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article
  3. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
  4. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
  5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cysteine metabolic process NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
homocysteine methyltransferase Met26

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1478398..1481172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018784.3 → NP_593352.1  homocysteine methyltransferase Met26 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593352.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P78818, Q9UT19
    Conserved Domains (3) summary
    PRK05222
    Location:1 → 764
    PRK05222; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional
    cd03312
    Location:3 → 370
    CIMS_N_terminal_like; CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme ...
    pfam01717
    Location:437 → 757
    Meth_synt_2; Cobalamin-independent synthase, Catalytic domain
Nucleotide Protein
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