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arg3 ornithine carbamoyltransferase Arg3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543593, updated on 18-Sep-2024

Summary

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Official Symbol
arg3
Official Full Name
ornithine carbamoyltransferase Arg3
Primary source
PomBase:SPAC4G9.10
Locus tag
SPOM_SPAC4G9.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See arg3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (2273921..2275516)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene N-acetyl-gamma-glutamyl-phosphate reductase/acetylglutamate kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytosine-mismatch-binding protein 1 Neighboring gene retromer complex arrestin related endocytic adaptor ubunit Vps26 Neighboring gene gluconokinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Thiol-independent action of mitochondrial thioredoxin to support the urea cycle of arginine biosynthesis in Schizosaccharomyces pombe. Song JY, et al. Eukaryot Cell, 2008 Dec. PMID 18849471, Free PMC Article
  2. Cloning and sequencing of arg3 and arg11 genes of Schizosaccharomyces pombe on a 10-kb DNA fragment. Heterologous expression and mitochondrial targeting of their translation products. Van Huffel C, et al. Eur J Biochem, 1992 Apr 1. PMID 1313366
  3. Mitochondrial respiration is required to provide amino acids during fermentative proliferation of fission yeast. Malecki M, et al. EMBO Rep, 2020 Nov 5. PMID 32896087, Free PMC Article
  4. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
  5. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables amino acid binding IEA
Inferred from Electronic Annotation
more info
  
enables ornithine carbamoyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ornithine carbamoyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in arginine biosynthetic process via ornithine EXP
Inferred from Experiment
more info
 PubMed 
involved_in arginine biosynthetic process via ornithine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in arginine biosynthetic process via ornithine IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in citrulline biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in urea cycle IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ornithine carbamoyltransferase Arg3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2273921..2275516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019124.3 → NP_593692.1  ornithine carbamoyltransferase Arg3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593692.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P31317
    Conserved Domains (3) summary
    COG0078
    Location:2 → 315
    ArgF; Ornithine carbamoyltransferase [Amino acid transport and metabolism]
    pfam00185
    Location:161 → 314
    OTCace; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
    pfam02729
    Location:9 → 154
    OTCace_N; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
Nucleotide Protein
Heading Accession and Version

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