U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cenpi centromere protein I [ Rattus norvegicus (Norway rat) ]

Gene ID: 25448, updated on 23-Jul-2024

Summary

Official Symbol
Cenpiprovided by RGD
Official Full Name
centromere protein Iprovided by RGD
Primary source
RGD:2631
See related
EnsemblRapid:ENSRNOG00000033335 AllianceGenome:RGD:2631
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
LRPR1; RNALRP; Fshprh1
Summary
Involved in follicle-stimulating hormone signaling pathway. Predicted to be located in cytosol; kinetochore; and nuclear body. Orthologous to human CENPI (centromere protein I). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 45.1), Thymus (RPKM 39.3) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Cenpi in Genome Data Viewer
Location:
Xq32
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (101809192..101860935)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (97515919..97567671)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (105147045..105198798)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene XK related, X-linked Neighboring gene tRNA methyltransferase 2 homolog B Neighboring gene transmembrane protein 35A Neighboring gene dystrophin related protein 2 Neighboring gene TATA-box binding protein associated factor 7-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in CENP-A containing chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in centromere complex assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in follicle-stimulating hormone signaling pathway IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in mitotic sister chromatid segregation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of inner kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of inner kinetochore IEA
Inferred from Electronic Annotation
more info
 
part_of inner kinetochore ISO
Inferred from Sequence Orthology
more info
 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
 
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
centromere protein I
Names
CENP-I
FSH primary response 1
FSH primary response protein 1
Follicle stimulating hormone primary response gene 1 (Leucine - rich primary resonse gene 1)
follicle-stimulating hormone primary response protein
leucine-rich primary response protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431555.1NP_001418484.1  centromere protein I

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
  2. NM_001431556.1NP_001418485.1  centromere protein I

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
  3. NM_001431557.1NP_001418486.1  centromere protein I

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
  4. NM_012955.1NP_037087.1  centromere protein I

    See identical proteins and their annotated locations for NP_037087.1

    Status: PROVISIONAL

    Source sequence(s)
    X90355
    UniProtKB/Swiss-Prot
    Q63517
    UniProtKB/TrEMBL
    A0A0G2K7E6
    Related
    ENSRNOP00000041317.4, ENSRNOT00000046288.6
    Conserved Domains (1) summary
    pfam07778
    Location:12515
    CENP-I; Mis6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    101809192..101860935
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006257217.5XP_006257279.1  centromere protein I isoform X1

    See identical proteins and their annotated locations for XP_006257279.1

    UniProtKB/TrEMBL
    A0A0G2K7E6, A6IVE9, F1LP20
    Conserved Domains (1) summary
    pfam07778
    Location:12515
    CENP-I; Mis6
  2. XM_006257215.5XP_006257277.1  centromere protein I isoform X1

    See identical proteins and their annotated locations for XP_006257277.1

    UniProtKB/TrEMBL
    A0A0G2K7E6, A6IVE9, F1LP20
    Conserved Domains (1) summary
    pfam07778
    Location:12515
    CENP-I; Mis6
  3. XM_039099502.2XP_038955430.1  centromere protein I isoform X2

    UniProtKB/TrEMBL
    A0A0G2K7E6
    Conserved Domains (1) summary
    pfam07778
    Location:12515
    CENP-I; Mis6
  4. XM_006257216.5XP_006257278.1  centromere protein I isoform X1

    See identical proteins and their annotated locations for XP_006257278.1

    UniProtKB/TrEMBL
    A0A0G2K7E6, A6IVE9, F1LP20
    Conserved Domains (1) summary
    pfam07778
    Location:12515
    CENP-I; Mis6