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Or2h1 olfactory receptor family 2 subfamily H member 1 [ Mus musculus (house mouse) ]

Gene ID: 258470, updated on 2-Nov-2024

Summary

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Official Symbol
Or2h1provided by MGI
Official Full Name
olfactory receptor family 2 subfamily H member 1provided by MGI
Primary source
MGI:MGI:2177474
See related
Ensembl:ENSMUSG00000095377 AllianceGenome:MGI:2177474
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr91; MOR256-20; bM573K1.3
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Or2h1 in Genome Data Viewer
Location:
17 B1; 17 19.16 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (37403022..37443877, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (37092845..37132991, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene gamma-aminobutyric acid type B receptor subunit 1 Neighboring gene STARR-seq mESC enhancer starr_42506 Neighboring gene predicted gene, 41579 Neighboring gene olfactory receptor family 2 subfamily H member 2 Neighboring gene olfactory receptor family 2 subfamily H member 2C Neighboring gene UPF0368 protein Cxorf26 homolog Neighboring gene STARR-seq mESC enhancer starr_42507 Neighboring gene olfactory receptor family 2 subfamily H member 1B Neighboring gene von Hippel-Lindau tumor suppressor-like, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex. Amadou C, et al. Hum Mol Genet, 2003 Nov 15. PMID 14506126
  2. Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Lewandowski JP, et al. Dev Biol, 2015 Oct 1. PMID 26238476, Free PMC Article
  3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 91
Names
G-protein coupled receptor
GA_x6K02T2PSCP-1533927-1532989
bM573K1.3 (novel 7 transmembrane receptor (rhodopsin family) (olfactory receptor LIKE) protein)
olfactory receptor MOR256-20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_182714.2 → NP_874373.2  olfactory receptor 91

    See identical proteins and their annotated locations for NP_874373.2

    Status: VALIDATED

    Source sequence(s)
    BC119413
    Consensus CDS
    CCDS50107.1
    UniProtKB/TrEMBL
    Q2VPE0, Q78NX2, Q7TRL3
    Related
    ENSMUSP00000129446.2, ENSMUST00000087144.5
    Conserved Domains (1) summary
    cd15947
    Location:23 → 292
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    37403022..37443877 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317477.3 → XP_017172966.1  olfactory receptor 91 isoform X1

    UniProtKB/TrEMBL
    Q2VPE0, Q78NX2, Q7TRL3
    Related
    ENSMUSP00000150298.2, ENSMUST00000217372.2
    Conserved Domains (1) summary
    cd15947
    Location:23 → 292
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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