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esr1 - estrogen receptor 1

Enables estradiol binding activity; nuclear estrogen receptor activity; and steroid hormone binding activity. Acts upstream of or within several processes, including cellular response to estrogen stimulus; posterior lateral line neuromast primordium migration; and response to estradiol. Predicted to be located in chromatin and cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including diencephalon; head; liver; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bone disease (multiple); breast cancer (multiple); type 2 diabetes mellitus; and vitiligo. Orthologous to human ESR1 (estrogen receptor 1). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to esr1

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Species Gene Architecture aa