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kl-3 - male fertility factor kl3

Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement and outer dynein arm assembly. Part of axonemal dynein complex. Is expressed in adult head; spermatogonium; and spermatozoon. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 3. Orthologous to human DNAH5 (dynein axonemal heavy chain 5). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa