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nduf-5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [ Caenorhabditis elegans ]

Gene ID: 266824, updated on 2-Nov-2024

Summary

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Official Symbol
nduf-5
Official Full Name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
Primary source
WormBase:WBGene00021839
Locus tag
CELE_Y54E10BL.5
See related
AllianceGenome:WB:WBGene00021839
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nduf-5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003279.8 (3001406..3002847, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SUPpressor of Rpm-1 Neighboring gene J domain-containing protein Neighboring gene CcoQ/FixQ family Cbb3-type cytochrome c oxidase assembly chaperone Neighboring gene Dual specificity mitogen-activated protein kinase kinase mek-2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The role of mitochondria in the life of the nematode, Caenorhabditis elegans. Tsang WY, et al. Biochim Biophys Acta, 2003 Jul 14. PMID 12853115
  2. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article
  3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
NP_491085.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3001406..3002847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058684.8 → NP_491085.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491085.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N3D9
    Conserved Domains (1) summary
    pfam10200
    Location:37 → 99
    Ndufs5; NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
Nucleotide Protein
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