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mab-23 DM domain-containing protein mab-23 [ Caenorhabditis elegans ]

Gene ID: 266926, updated on 2-Nov-2024

Summary

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Official Symbol
mab-23
Official Full Name
DM domain-containing protein mab-23
Primary source
WormBase:WBGene00003114
Locus tag
CELE_C32C4.5
See related
AllianceGenome:WB:WBGene00003114
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metal ion binding activity and sequence-specific DNA binding activity. Involved in several processes, including neuron fate determination; regulation of male mating behavior; and regulation of nematode male tail tip morphogenesis. Located in nucleus. Is expressed in several structures, including U cell; hermaphrodite gonad; neurons; tail hypodermis; and ventral nerve cord. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mab-23 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (10633058..10635525)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BTB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural variation and copulatory plug formation in Caenorhabditis elegans. Hodgkin J, et al. Genetics, 1997 May. PMID 9136008, Free PMC Article
  2. Multiple doublesex-related genes specify critical cell fates in a C. elegans male neural circuit. Siehr MS, et al. PLoS One, 2011. PMID 22069471, Free PMC Article
  3. Riddle DL, et al. , 1997. PMID 21413221
  4. C. elegans: social interactions in a "nonsocial" animal. Ardiel EL, et al. Adv Genet, 2009. PMID 20109657
  5. Copulation in C. elegans males requires a nuclear hormone receptor. Shan G, et al. Dev Biol, 2008 Oct 1. PMID 18652814

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in neuron fate determination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of male mating behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of nematode male tail tip morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DM domain-containing protein mab-23
NP_001041089.1
  • Confirmed by transcript evidence
NP_001041090.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10633058..10635525
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047624.2 → NP_001041089.1  DM domain-containing protein mab-23 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041089.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5ECK3, Q1NZ22
    Conserved Domains (1) summary
    cl02557
    Location:6 → 55
    DM; DM DNA binding domain

  2. NM_001047625.1 → NP_001041090.1  DM domain-containing protein mab-23 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041090.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q1NZ22
    Conserved Domains (1) summary
    COG0017
    Location:13 → 64
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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