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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001077707.1 → NP_001071175.1 E3 ubiquitin-protein ligase SHPRH isoform a
See identical proteins and their annotated locations for NP_001071175.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
AK082160, BB650602, BC055003, BP757728
- Consensus CDS
-
CCDS35838.1
- UniProtKB/Swiss-Prot
- Q7TPQ3, Q7TQ27, Q7TQ28, Q7TQ29, Q8BKE2, Q8BUW0, Q922Q3
- Related
- ENSMUSP00000039422.7, ENSMUST00000044053.13
- Conserved Domains (7) summary
-
- COG0553
Location:1314 → 1669
- HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
- cd15547
Location:651 → 697
- PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
- cd16569
Location:1420 → 1470
- RING-HC_SHPRH; RING finger, HC subclass, found in SNF2 histone-linker PHD finger RING finger helicase (SHPRH) and similar proteins
- cd18793
Location:1499 → 1624
- SF2_C_SNF; C-terminal helicase domain of the SNF family helicases
- cd18070
Location:693 → 894
- DEXQc_SHPRH; DEXQ-box helicase domain of SHPRH
- pfam00538
Location:435 → 506
- Linker_histone; linker histone H1 and H5 family
- cl28899
Location:299 → 419
- DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
-
NM_001284354.1 → NP_001271283.1 E3 ubiquitin-protein ligase SHPRH isoform c
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks two exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform c which is shorter and has a distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
AK044720, AK053448, BB650602, BC055003
- Consensus CDS
-
CCDS70003.1
- UniProtKB/Swiss-Prot
-
Q7TPQ3
- Related
- ENSMUSP00000132870.2, ENSMUST00000159541.8
- Conserved Domains (7) summary
-
- COG0553
Location:1314 → 1619
- HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
- cd00162
Location:1423 → 1473
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- cd15547
Location:651 → 697
- PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
- pfam00176
Location:707 → 978
- SNF2_N; SNF2 family N-terminal domain
- pfam00271
Location:1504 → 1613
- Helicase_C; Helicase conserved C-terminal domain
- pfam00538
Location:435 → 506
- Linker_histone; linker histone H1 and H5 family
- pfam13424
Location:1011 → 1095
- TPR_12; Tetratricopeptide repeat
-
NM_172937.3 → NP_766525.3 E3 ubiquitin-protein ligase SHPRH isoform b
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks two exons and its transcription extends past a splice site that is used in variant 1, resulting in an immediate translation termination and a distinct 3' UTR compared to variant 1. It encodes isoform b which is truncated at the C-terminus, compared to isoform a.
- Source sequence(s)
-
AC158601, AK044720, AK082160, BB650602, BC055003
- Consensus CDS
-
CCDS35839.1
- UniProtKB/Swiss-Prot
-
Q7TPQ3
- Related
- ENSMUSP00000125849.2, ENSMUST00000054814.14
- Conserved Domains (7) summary
-
- COG0553
Location:1314 → 1616
- HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
- cd00162
Location:1423 → 1473
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- cd15547
Location:651 → 697
- PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
- pfam00176
Location:707 → 978
- SNF2_N; SNF2 family N-terminal domain
- pfam00271
Location:1504 → 1613
- Helicase_C; Helicase conserved C-terminal domain
- pfam00538
Location:435 → 506
- Linker_histone; linker histone H1 and H5 family
- pfam13424
Location:1011 → 1095
- TPR_12; Tetratricopeptide repeat
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000076.7 Reference GRCm39 C57BL/6J
- Range
-
11024765..11093339
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006512740.5 → XP_006512803.1 E3 ubiquitin-protein ligase SHPRH isoform X1
See identical proteins and their annotated locations for XP_006512803.1
- UniProtKB/Swiss-Prot
- Q7TPQ3, Q7TQ27, Q7TQ28, Q7TQ29, Q8BKE2, Q8BUW0, Q922Q3
- Conserved Domains (7) summary
-
- COG0553
Location:1314 → 1669
- HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
- cd15547
Location:651 → 697
- PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
- cd16569
Location:1420 → 1470
- RING-HC_SHPRH; RING finger, HC subclass, found in SNF2 histone-linker PHD finger RING finger helicase (SHPRH) and similar proteins
- cd18793
Location:1499 → 1624
- SF2_C_SNF; C-terminal helicase domain of the SNF family helicases
- cd18070
Location:693 → 894
- DEXQc_SHPRH; DEXQ-box helicase domain of SHPRH
- pfam00538
Location:435 → 506
- Linker_histone; linker histone H1 and H5 family
- cl28899
Location:299 → 419
- DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
RNA
-
XR_871438.4 RNA Sequence
-
XR_380065.5 RNA Sequence
- Related
-
ENSMUST00000159810.8