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Krt222 keratin 222 [ Mus musculus (house mouse) ]

Gene ID: 268481, updated on 4-Nov-2024

Summary

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Official Symbol
Krt222provided by MGI
Official Full Name
keratin 222provided by MGI
Primary source
MGI:MGI:2442728
See related
Ensembl:ENSMUSG00000035849 AllianceGenome:MGI:2442728
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6330509G02Rik
Summary
Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Orthologous to human KRT222 (keratin 222). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in cerebellum adult (RPKM 8.2), cortex adult (RPKM 5.5) and 5 other tissues See more
Orthologs
human all
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Genomic context

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See Krt222 in Genome Data Viewer
Location:
11 D; 11 62.92 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99123587..99134973, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (99232761..99244147, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32249 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 Neighboring gene STARR-seq mESC enhancer starr_30702 Neighboring gene STARR-positive B cell enhancer ABC_E8451 Neighboring gene predicted gene, 32385 Neighboring gene keratin 24 Neighboring gene STARR-seq mESC enhancer starr_30703 Neighboring gene keratin 25

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. New consensus nomenclature for mammalian keratins. Schweizer J, et al. J Cell Biol, 2006 Jul 17. PMID 16831889, Free PMC Article
  2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • MGC100296

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
keratin-like protein KRT222

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361584.1 → NP_001348513.1  keratin-like protein KRT222 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK044068, BB850745, BC079890
    Consensus CDS
    CCDS88251.1
    Related
    ENSMUSP00000044561.7, ENSMUST00000038214.7
    Conserved Domains (1) summary
    pfam00038
    Location:2 → 109
    Filament; Intermediate filament protein

  2. NM_172946.3 → NP_766534.1  keratin-like protein KRT222 isoform 1

    See identical proteins and their annotated locations for NP_766534.1

    Status: VALIDATED

    Source sequence(s)
    AK031954, BB850745, BC079890
    Consensus CDS
    CCDS25375.1
    UniProtKB/Swiss-Prot
    Q3UU52, Q68FD8, Q8CCX5
    Related
    ENSMUSP00000099421.4, ENSMUST00000103132.10
    Conserved Domains (3) summary
    pfam07889
    Location:21 → 83
    DUF1664; Protein of unknown function (DUF1664)
    cd16269
    Location:118 → 131
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:46 → 146
    GBP_C; Guanylate-binding protein, C-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    99123587..99134973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CCX5.1 GenPept UniProtKB/Swiss-Prot:Q8CCX5

Gene LinkOut

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