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Pcnx2 pecanex homolog 2 [ Mus musculus (house mouse) ]

Gene ID: 270109, updated on 28-Oct-2024

Summary

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Official Symbol
Pcnx2provided by MGI
Official Full Name
pecanex homolog 2provided by MGI
Primary source
MGI:MGI:2445010
See related
Ensembl:ENSMUSG00000060212 AllianceGenome:MGI:2445010
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pcnxl2; mKIAA0435; A830048P05; E330039K12Rik
Summary
Predicted to be located in membrane. Orthologous to human PCNX2 (pecanex 2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in cortex adult (RPKM 9.1), frontal lobe adult (RPKM 7.7) and 8 other tissues See more
Orthologs
human all
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Genomic context

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See Pcnx2 in Genome Data Viewer
Location:
8 E2; 8 73.65 cM
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (126478243..126625056, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (125751504..125898332, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23044 Neighboring gene STARR-seq mESC enhancer starr_23045 Neighboring gene predicted gene, 39283 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:128265368-128265564 Neighboring gene nucleoside-triphosphatase, cancer-related Neighboring gene predicted gene, 39285 Neighboring gene predicted gene, 39284 Neighboring gene predicted gene, 51603 Neighboring gene predicted gene, 46061 Neighboring gene STARR-seq mESC enhancer starr_23048 Neighboring gene STARR-seq mESC enhancer starr_23049 Neighboring gene RIKEN cDNA A730098A19 gene Neighboring gene mitogen-activated protein kinase kinase kinase 21 Neighboring gene STARR-positive B cell enhancer mm9_chr8:128474175-128474476 Neighboring gene predicted gene, 31069

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy. Frankel WN, et al. PLoS Genet, 2014 Jul. PMID 25010494, Free PMC Article
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Clone Names

  • KIAA0435

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
pecanex-like protein 2
Names
pecanex homolog protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175561.4 → NP_780770.2  pecanex-like protein 2

    See identical proteins and their annotated locations for NP_780770.2

    Status: VALIDATED

    Source sequence(s)
    AK043903, AK220342, BC068235, CJ111064
    Consensus CDS
    CCDS52708.1
    UniProtKB/Swiss-Prot
    A2RT20, Q5DU28, Q8BRN0, Q8C2V1, Q8CDD2
    Related
    ENSMUSP00000042294.7, ENSMUST00000047239.13
    Conserved Domains (1) summary
    pfam05041
    Location:1603 → 1826
    Pecanex_C; Pecanex protein (C-terminus)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    126478243..126625056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248395.4 → XP_011246697.1  pecanex-like protein 2 isoform X1

    Conserved Domains (2) summary
    PHA03307
    Location:145 → 501
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1610 → 1835
    Pecanex_C; Pecanex protein (C-terminus)

  2. XM_036154083.1 → XP_036009976.1  pecanex-like protein 2 isoform X3

    Conserved Domains (2) summary
    PHA03307
    Location:36 → 392
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1494 → 1719
    Pecanex_C; Pecanex protein (C-terminus)

  3. XM_011248396.3 → XP_011246698.1  pecanex-like protein 2 isoform X2

    Conserved Domains (2) summary
    PHA03307
    Location:36 → 392
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1501 → 1726
    Pecanex_C; Pecanex protein (C-terminus)

  4. XM_006531060.1 → XP_006531123.1  pecanex-like protein 2 isoform X4

    Related
    ENSMUST00000120589.8
    Conserved Domains (1) summary
    pfam05041
    Location:726 → 951
    Pecanex_C; Pecanex protein (C-terminus)

RNA

  1. XR_003947294.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5DU28.2 GenPept UniProtKB/Swiss-Prot:Q5DU28

Gene LinkOut

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