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Tcl1b3 T cell leukemia/lymphoma 1B, 3 [ Mus musculus (house mouse) ]

Gene ID: 27378, updated on 2-Nov-2024

Summary

Official Symbol
Tcl1b3provided by MGI
Official Full Name
T cell leukemia/lymphoma 1B, 3provided by MGI
Primary source
MGI:MGI:1351600
See related
Ensembl:ENSMUSG00000068940 AllianceGenome:MGI:1351600
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable protein kinase binding activity and protein serine/threonine kinase activator activity. Predicted to be involved in intracellular signal transduction. Orthologous to human TCL1B (TCL1 family AKT coactivator B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward ovary adult (RPKM 1.3) See more
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Genomic context

See Tcl1b3 in Genome Data Viewer
Location:
12 E; 12 55.25 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (105157304..105161658)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (105191045..105195399)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene T cell leukemia/lymphoma 1B, 1 Neighboring gene T cell leukemia/lymphoma 1B, 5 Neighboring gene T cell leukemia/lymphoma 1B, 4 Neighboring gene T cell lymphoma breakpoint 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein serine/threonine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular signal transduction ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013772.2NP_038800.1  protein TCL1B3

    See identical proteins and their annotated locations for NP_038800.1

    Status: PROVISIONAL

    Source sequence(s)
    BC120575
    Consensus CDS
    CCDS36547.1
    UniProtKB/Swiss-Prot
    P56842
    UniProtKB/TrEMBL
    Q0VBM6
    Related
    ENSMUSP00000088512.5, ENSMUST00000090990.6
    Conserved Domains (1) summary
    pfam01840
    Location:1118
    TCL1_MTCP1; TCL1/MTCP1 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    105157304..105161658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)