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Spin2c spindlin family, member 2C [ Mus musculus (house mouse) ]

Gene ID: 278240, updated on 28-Oct-2024

Summary

Official Symbol
Spin2cprovided by MGI
Official Full Name
spindlin family, member 2Cprovided by MGI
Primary source
MGI:MGI:3605548
See related
Ensembl:ENSMUSG00000046550 AllianceGenome:MGI:3605548
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Spin2; SPIN-2C
Summary
Predicted to enable methylated histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be active in cytosol and nucleoplasm. Is expressed in embryo. Orthologous to human SPIN2A (spindlin family member 2A) and SPIN2B (spindlin family member 2B). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in placenta adult (RPKM 4.6), genital fat pad adult (RPKM 3.9) and 14 other tissues See more
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Genomic context

See Spin2c in Genome Data Viewer
Location:
X F3; X 72.38 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (152615246..152617239)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (153832004..153834243)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene negative regulator of P-body association Neighboring gene SMT3 suppressor of mif two 3 homolog 1, pseudogene (S. cerevisiae) Neighboring gene STARR-seq mESC enhancer starr_48124 Neighboring gene predicted gene, 25895 Neighboring gene spermatogenesis associated multipass transmembrane protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC93001

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables methylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables methylated histone binding ISO
Inferred from Sequence Orthology
more info
 
enables methylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in gamete generation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
spindlin-2C
Names
SPIN-2
spindlin family, member 2
spindlin-2
spindlin-like protein 2
spindlin-like protein 2C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005370.2NP_001005370.1  spindlin-2C

    See identical proteins and their annotated locations for NP_001005370.1

    Status: VALIDATED

    Source sequence(s)
    AL831725
    Consensus CDS
    CCDS30485.1
    UniProtKB/Swiss-Prot
    Q6NVE3
    Related
    ENSMUSP00000059499.9, ENSMUST00000049999.9
    Conserved Domains (1) summary
    pfam02513
    Location:4897
    Spin-Ssty; Spin/Ssty Family
  2. NM_001418374.1NP_001405303.1  spindlin-2C

    Status: VALIDATED

    Source sequence(s)
    AL831725
    UniProtKB/Swiss-Prot
    Q6NVE3
  3. NM_001418375.1NP_001405304.1  spindlin-2C

    Status: VALIDATED

    Source sequence(s)
    AL831725
    UniProtKB/Swiss-Prot
    Q6NVE3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    152615246..152617239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)