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GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) [ Bos taurus (domestic cattle) ]

Gene ID: 281780, updated on 10-Oct-2024

Summary

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Gene symbol
GGTA1
Gene description
glycoprotein alpha-galactosyltransferase 1 (inactive)
See related
BGD:BT21137; Ensembl:ENSBTAG00000012090
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See GGTA1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (92316193..92394954, complement)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene N-acetyllactosaminide alpha-1,3-galactosyltransferase-like 1 Neighboring gene glycoprotein galactosyltransferase alpha 1, 3-like Neighboring gene uncharacterized LOC132346630 Neighboring gene DAB2 interacting protein Neighboring gene uncharacterized LOC112448832

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substrate-assisted and nucleophilically assisted catalysis in bovine α1,3-galactosyltransferase. Mechanistic implications for retaining glycosyltransferases. Gómez H, et al. J Am Chem Soc, 2013 May 8. PMID 23578032
  2. Structural basis of ordered binding of donor and acceptor substrates to the retaining glycosyltransferase, alpha-1,3-galactosyltransferase. Boix E, et al. J Biol Chem, 2002 Aug 2. PMID 12011052
  3. Structure of UDP complex of UDP-galactose:beta-galactoside-alpha -1,3-galactosyltransferase at 1.53-A resolution reveals a conformational change in the catalytically important C terminus. Boix E, et al. J Biol Chem, 2001 Dec 21. PMID 11592969
  4. Bovine alpha 1----3-galactosyltransferase: isolation and characterization of a cDNA clone. Identification of homologous sequences in human genomic DNA. Joziasse DH, et al. J Biol Chem, 1989 Aug 25. PMID 2503516
  5. Bovine alpha1,3-galactosyltransferase catalytic domain structure and its relationship with ABO histo-blood group and glycosphingolipid glycosyltransferases. Gastinel LN, et al. EMBO J, 2001 Feb 15. PMID 11179209, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid glycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
N-acetyllactosaminide alpha-1,3-galactosyltransferase
Names
UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase
alpha-galactosyltransferase 1 (glycoprotein)
alpha1,3-galactosyltransferase
galactosyltransferase
NP_803477.1
XP_005212979.2
XP_005212980.1
XP_005212981.1
XP_010808472.2
XP_010808474.1
XP_015329017.1
XP_024854041.1
XP_024854045.1
XP_024854049.1
XP_059746986.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177511.2 → NP_803477.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase

    See identical proteins and their annotated locations for NP_803477.1

    Status: PROVISIONAL

    Source sequence(s)
    J04989
    UniProtKB/Swiss-Prot
    P14769
    UniProtKB/TrEMBL
    A0AAA9T516
    Related
    ENSBTAP00000016033.2, ENSBTAT00000016033.3
    Conserved Domains (1) summary
    pfam03414
    Location:85 → 366
    Glyco_transf_6; Glycosyltransferase family 6

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    92316193..92394954 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024998281.2 → XP_024854049.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X7

    UniProtKB/TrEMBL
    A0AAA9T516
    Conserved Domains (1) summary
    cl11394
    Location:96 → 320
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. XM_005212923.5 → XP_005212980.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X3

    See identical proteins and their annotated locations for XP_005212980.1

    UniProtKB/Swiss-Prot
    P14769
    UniProtKB/TrEMBL
    A0AAA9T516
    Conserved Domains (1) summary
    pfam03414
    Location:85 → 366
    Glyco_transf_6; Glycosyltransferase family 6

  3. XM_010810170.4 → XP_010808472.2  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X4

    UniProtKB/TrEMBL
    A0AAF7AT15
    Related
    ENSBTAP00000074297.2, ENSBTAT00000084155.2

  4. XM_005212922.5 → XP_005212979.2  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X3

    UniProtKB/Swiss-Prot
    P14769

  5. XM_024998277.2 → XP_024854045.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X3

    UniProtKB/Swiss-Prot
    P14769
    UniProtKB/TrEMBL
    A0AAA9T516
    Conserved Domains (1) summary
    pfam03414
    Location:85 → 366
    Glyco_transf_6; Glycosyltransferase family 6

  6. XM_024998273.2 → XP_024854041.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X1

    Conserved Domains (1) summary
    cl11394
    Location:293 → 517
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  7. XM_059891003.1 → XP_059746986.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X2

  8. XM_005212924.5 → XP_005212981.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X3

    See identical proteins and their annotated locations for XP_005212981.1

    UniProtKB/Swiss-Prot
    P14769
    UniProtKB/TrEMBL
    A0AAA9T516
    Conserved Domains (1) summary
    pfam03414
    Location:85 → 366
    Glyco_transf_6; Glycosyltransferase family 6

  9. XM_015473531.3 → XP_015329017.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X5

    UniProtKB/TrEMBL
    A0AAA9S3W0, A0AAA9T516
    Related
    ENSBTAP00000078478.1, ENSBTAT00000124589.1
    Conserved Domains (1) summary
    pfam03414
    Location:134 → 417
    Glyco_transf_6; Glycosyltransferase family 6

  10. XM_010810172.4 → XP_010808474.1  N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X6

    UniProtKB/TrEMBL
    A0AAA9T516
    Conserved Domains (1) summary
    pfam03414
    Location:127 → 410
    Glyco_transf_6; Glycosyltransferase family 6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P14769.1 GenPept UniProtKB/Swiss-Prot:P14769

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