IGHV4-31 immunoglobulin heavy variable 4-31 [Homo sapiens (human)] - Gene

Summary

Official Symbol: IGHV4-31provided by HGNC
Official Full Name: immunoglobulin heavy variable 4-31provided by HGNC
Primary source: HGNC:HGNC:5649
See related: IMGT/GENE-DB:IGHV4-31; AllianceGenome:HGNC:5649
Gene type: other
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: IGHV431
Summary: Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: not in current annotation release
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Annotation release	Status	Assembly	Chr	Location
105	latest, but not current	GRCh37.p13 (GCF_000001405.25)	14	NC_000014.8 (106805207..106805644, complement)
105	latest, but not current	HuRef (GCF_000002125.1)	14	AC_000146.1 (86942185..86942622, complement)
105	latest, but not current	CHM1_1.1 (GCF_000306695.2)	14	NC_018925.2 (106686239..106686676, complement)

Immunoglobulin gamma heavy chain gene with somatic hypermutation is frequently expressed in acute myeloid leukemia.
Title: Immunoglobulin gamma heavy chain gene with somatic hypermutation is frequently expressed in acute myeloid leukemia.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables antigen binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in immunoglobulin mediated immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
part_of immunoglobulin complex	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info