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Smim3 small integral membrane protein 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 286910, updated on 17-Aug-2024

Summary

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Official Symbol
Smim3provided by RGD
Official Full Name
small integral membrane protein 3provided by RGD
Primary source
RGD:628864
See related
EnsemblRapid:ENSRNOG00000019536 AllianceGenome:RGD:628864
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nid67
Summary
Predicted to enable identical protein binding activity. Predicted to be integral component of membrane. Orthologous to human SMIM3 (small integral membrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 132.0), Adrenal (RPKM 114.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
18q12.1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (56200458..56252778, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (53930019..53982339, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (55744809..55797186, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene interferon-gamma-inducible GTPase 2 like 2 Neighboring gene interferon-gamma-inducible GTPase 2 like, pseudogene 1 Neighboring gene dynactin subunit 4 Neighboring gene RNA binding motif protein 22 Neighboring gene myozenin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. NID67, a small putative membrane protein, is preferentially induced by NGF in PC12 pheochromocytoma cells. Vician L, et al. J Neurosci Res, 2001 Apr 15. PMID 11288140
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in nervous system development NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
small integral membrane protein 3
Names
NGF-induced differentiation clone 67 protein
putative small membrane protein NID67
small membrane protein NID67

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173126.3 → NP_775149.1  small integral membrane protein 3

    See identical proteins and their annotated locations for NP_775149.1

    Status: VALIDATED

    Source sequence(s)
    AF313411, BC070515, EV780394
    UniProtKB/Swiss-Prot
    Q99PE6
    UniProtKB/TrEMBL
    A6IXB1
    Related
    ENSRNOP00000026426.3, ENSRNOT00000026426.7
    Conserved Domains (1) summary
    pfam17307
    Location:1 → 60
    Smim3; Small integral membrane protein 3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    56200458..56252778 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600864.3 → XP_017456353.1  small integral membrane protein 3 isoform X6

    UniProtKB/Swiss-Prot
    Q99PE6
    UniProtKB/TrEMBL
    A6IXB1
    Conserved Domains (1) summary
    pfam17307
    Location:1 → 60
    Smim3; Small integral membrane protein 3

  2. XM_039096614.2 → XP_038952542.1  small integral membrane protein 3 isoform X6

    UniProtKB/Swiss-Prot
    Q99PE6
    UniProtKB/TrEMBL
    A6IXB1
    Conserved Domains (1) summary
    pfam17307
    Location:1 → 60
    Smim3; Small integral membrane protein 3

  3. XM_039096609.2 → XP_038952537.1  small integral membrane protein 3 isoform X1

    Conserved Domains (1) summary
    pfam17307
    Location:57 → 116
    Smim3; Small integral membrane protein 3

  4. XM_039096613.2 → XP_038952541.1  small integral membrane protein 3 isoform X6

    UniProtKB/Swiss-Prot
    Q99PE6
    UniProtKB/TrEMBL
    A6IXB1
    Conserved Domains (1) summary
    pfam17307
    Location:1 → 60
    Smim3; Small integral membrane protein 3

  5. XM_063277153.1 → XP_063133223.1  small integral membrane protein 3 isoform X6

    UniProtKB/Swiss-Prot
    Q99PE6
    UniProtKB/TrEMBL
    A6IXB1

  6. XM_063277149.1 → XP_063133219.1  small integral membrane protein 3 isoform X3

  7. XM_006254769.4 → XP_006254831.1  small integral membrane protein 3 isoform X6

    See identical proteins and their annotated locations for XP_006254831.1

    UniProtKB/Swiss-Prot
    Q99PE6
    UniProtKB/TrEMBL
    A6IXB1
    Conserved Domains (1) summary
    pfam17307
    Location:1 → 60
    Smim3; Small integral membrane protein 3

  8. XM_063277151.1 → XP_063133221.1  small integral membrane protein 3 isoform X5

  9. XM_063277150.1 → XP_063133220.1  small integral membrane protein 3 isoform X4

  10. XM_063277152.1 → XP_063133222.1  small integral membrane protein 3 isoform X5

  11. XM_063277146.1 → XP_063133216.1  small integral membrane protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8I6GG85

  12. XM_063277148.1 → XP_063133218.1  small integral membrane protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8I6GG85

  13. XM_017600863.3 → XP_017456352.1  small integral membrane protein 3 isoform X6

    UniProtKB/Swiss-Prot
    Q99PE6
    UniProtKB/TrEMBL
    A6IXB1
    Conserved Domains (1) summary
    pfam17307
    Location:1 → 60
    Smim3; Small integral membrane protein 3
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99PE6.1 GenPept UniProtKB/Swiss-Prot:Q99PE6

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