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creA transcription factor creA [ Aspergillus nidulans FGSC A4 ]

Gene ID: 2870784, updated on 21-Jun-2023

Summary

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Gene symbol
creA
Gene description
transcription factor creA
Locus tag
ANIA_06195
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Aspergillus nidulans FGSC A4 (strain: FGSC A4)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Nidulantes
Old locus tag
AN6195.4; AN6195.2
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Genomic context

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See creA in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_066257.1 (965719..967720)

Chromosome I - NC_066257.1Genomic Context describing neighboring genes Neighboring gene dynein regulator nudF Neighboring gene protein sapA Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_066257.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Carbon Catabolite Repression in Filamentous Fungi Is Regulated by Phosphorylation of the Transcription Factor CreA. de Assis LJ, et al. mBio, 2021 Jan 5. PMID 33402538, Free PMC Article
  2. The interaction of induction, repression and starvation in the regulation of extracellular proteases in Aspergillus nidulans: evidence for a role for CreA in the response to carbon starvation. Katz ME, et al. Curr Genet, 2008 Jul. PMID 18512059
  3. Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol. Mogensen J, et al. Fungal Genet Biol, 2006 Aug. PMID 16698295
  4. Proteins interacting with CreA and CreB in the carbon catabolite repression network in Aspergillus nidulans. Alam MA, et al. Curr Genet, 2017 Aug. PMID 27915380
  5. The CreB deubiquitinating enzyme does not directly target the CreA repressor protein in Aspergillus nidulans. Alam MA, et al. Curr Genet, 2017 Aug. PMID 27878624

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Carbon Catabolite Repression in Filamentous Fungi Is Regulated by Phosphorylation of the Transcription Factor CreA.
    Title: Carbon Catabolite Repression in Filamentous Fungi Is Regulated by Phosphorylation of the Transcription Factor CreA.
  2. CreA is not a direct target of CreB, and nor are proteins that form part of a stable complex with CreA a target of CreB. These results open up new questions regarding the molecular mechanism of CreA repressing activity, and how the ubiquitination pathway involving CreB interacts with this regulatory network
    Title: The CreB deubiquitinating enzyme does not directly target the CreA repressor protein in Aspergillus nidulans.
  3. Hir3 was present in repressing conditions for CreA and in both growth conditions for CreB, suggesting that Hir3, or proteins interacting with Hir3, could be a possible target of CreB
    Title: Proteins interacting with CreA and CreB in the carbon catabolite repression network in Aspergillus nidulans.
  4. Mutations in the creA, creB and creC genes increased extracellular protease levels in medium lacking a carbon source suggesting that they may have a role in the response to carbon starvation as well as carbon catabolite repression.
    Title: The interaction of induction, repression and starvation in the regulation of extracellular proteases in Aspergillus nidulans: evidence for a role for CreA in the response to carbon starvation.
  5. overview of genes either affected directly or indirectly by CreA, genes affected by the carbon source and genes affected by both CreA as well as the carbon source
    Title: Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
transcription factor creA
XP_663799.1
  • transcript_id=CADANIAT00006813

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_066257.1 Reference assembly

    Range
    965719..967720
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_658707.2 → XP_663799.1  TPA: transcription factor creA [Aspergillus nidulans FGSC A4]

    See identical proteins and their annotated locations for XP_663799.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    C8V211, Q01981, Q5AZT5
    Conserved Domains (4) summary
    COG5048
    Location:56 → 358
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:66 → 86
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:64 → 86
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:81 → 105
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q01981.1

Gene LinkOut

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Molecular Biology Databases
Research Materials