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Rpusd1 RNA pseudouridine synthase domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287148, updated on 2-Nov-2024

Summary

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Official Symbol
Rpusd1provided by RGD
Official Full Name
RNA pseudouridine synthase domain containing 1provided by RGD
Primary source
RGD:1304934
See related
EnsemblRapid:ENSRNOG00000023639 AllianceGenome:RGD:1304934
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1304934
Summary
Predicted to enable pseudouridine synthase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis. Orthologous to human RPUSD1 (RNA pseudouridine synthase domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 49.9), Thymus (RPKM 34.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rpusd1 in Genome Data Viewer
Location:
10q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15255806..15259730)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14751310..14755213)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15099104..15102968)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095315 Neighboring gene G protein subunit gamma 13 Neighboring gene chromosome transmission fidelity factor 18 Neighboring gene mesothelin-like Neighboring gene mesothelin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables pseudouridine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in enzyme-directed rRNA pseudouridine synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA pseudouridylate synthase domain-containing protein 1
Names
RNA pseudouridylate synthase domain containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105774.1 → NP_001099244.1  RNA pseudouridylate synthase domain-containing protein 1

    See identical proteins and their annotated locations for NP_001099244.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A6HD41, B1WC14, F7F6F2
    Conserved Domains (1) summary
    cd02869
    Location:18 → 215
    PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15255806..15259730
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006245937.5 → XP_006245999.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006245999.1

    UniProtKB/TrEMBL
    A6HD41, B1WC14, F7F6F2
    Related
    ENSRNOP00000015206.5, ENSRNOT00000015206.8
    Conserved Domains (1) summary
    cd02869
    Location:18 → 215
    PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

  2. XM_063268569.1 → XP_063124639.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X2

  3. XM_039085363.2 → XP_038941291.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    cd02869
    Location:18 → 170
    PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family
Nucleotide Protein Strain
Heading Accession and Version

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