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B3galt5 Beta-1,3-galactosyltransferase 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288161, updated on 14-Nov-2024

Summary

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Official Symbol
B3galt5provided by RGD
Official Full Name
Beta-1,3-galactosyltransferase 5provided by RGD
Primary source
RGD:1306727
See related
EnsemblRapid:ENSRNOG00000030983 AllianceGenome:RGD:1306727
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to act upstream of or within response to bacterium. Predicted to be active in Golgi membrane. Orthologous to human B3GALT5 (beta-1,3-galactosyltransferase 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 52.8), Brain (RPKM 24.4) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See B3galt5 in Genome Data Viewer
Location:
11q11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (49053959..49100398)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (35584273..35630922)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (36638067..36683915)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene lebercilin LCA5 like Neighboring gene SH3 domain binding glutamate-rich protein Neighboring gene microRNA 6325 Neighboring gene immunoglobulin superfamily, member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Association between expression levels of CA 19-9 and N-acetylglucosamine-beta;1,3-galactosyltransferase 5 gene in human pancreatic cancer tissue. Hayashi N, et al. Pathobiology, 2004. PMID 14555842
  2. Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. Hu YH, et al. BMC Genomics, 2006 Jun 16. PMID 16780588, Free PMC Article
  3. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within response to bacterium ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
beta-1,3-galactosyltransferase 5
Names
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
NP_001099357.1
XP_017453417.1
XP_017453418.1
XP_063126476.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105887.3 → NP_001099357.1  beta-1,3-galactosyltransferase 5

    See identical proteins and their annotated locations for NP_001099357.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    UniProtKB/TrEMBL
    A6KPR5, D4AB20
    Related
    ENSRNOP00000045319.3, ENSRNOT00000050178.6
    Conserved Domains (1) summary
    cl21608
    Location:69 → 259
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    49053959..49100398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063270406.1 → XP_063126476.1  beta-1,3-galactosyltransferase 5 isoform X1

    UniProtKB/TrEMBL
    A6KPR5, D4AB20
    Related
    ENSRNOP00000082456.1, ENSRNOT00000119017.2

  2. XM_017597929.3 → XP_017453418.1  beta-1,3-galactosyltransferase 5 isoform X1

    UniProtKB/TrEMBL
    A6KPR5, D4AB20
    Conserved Domains (1) summary
    cl21608
    Location:69 → 259
    Galactosyl_T; Galactosyltransferase

  3. XM_017597928.3 → XP_017453417.1  beta-1,3-galactosyltransferase 5 isoform X1

    UniProtKB/TrEMBL
    A6KPR5, D4AB20
    Related
    ENSRNOP00000106597.1, ENSRNOT00000163103.1
    Conserved Domains (1) summary
    cl21608
    Location:69 → 259
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein Strain
Heading Accession and Version

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