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Crybg3 crystallin beta-gamma domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288204, updated on 2-Nov-2024

Summary

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Symbol
Crybg3provided by RGD
Full Name
crystallin beta-gamma domain containing 3provided by RGD
Primary source
RGD:1305628
See related
EnsemblRapid:ENSRNOG00000045728 AllianceGenome:RGD:1305628
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305628; AABR07033887.1
Summary
Predicted to enable protein kinase A binding activity. Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Predicted to be part of protein-containing complex. Orthologous to human CRYBG3 (crystallin beta-gamma domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 321.6), Lung (RPKM 163.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Crybg3 in Genome Data Viewer
Location:
11q12
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (54218399..54330962)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (40749198..40861753)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (42895610..43006568)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene Eph receptor A6 Neighboring gene U7 small nuclear RNA Neighboring gene ADP-ribosylation factor like GTPase 6 Neighboring gene NLR family, pyrin domain containing 4A, pseudogene 1 Neighboring gene uncharacterized LOC134480985 Neighboring gene ribosomal oxygenase 2 Neighboring gene gamma-aminobutyric acid type A receptor subunit rho3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A systematic evaluation of protein kinase A-A-kinase anchoring protein interaction motifs. Burgers PP, et al. Biochemistry, 2015 Jan 13. PMID 25097019
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein kinase A binding ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of eye lens IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in lens development in camera-type eye IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in visual perception IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
beta/gamma crystallin domain-containing protein 3; very large A-kinase anchor protein
Names
beta-gamma crystallin domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    54218399..54330962
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_213639.11 → XP_213639.6  very large A-kinase anchor protein

    See identical proteins and their annotated locations for XP_213639.6

    UniProtKB/TrEMBL
    A0A8I6A3B0, M0RDY6
    Related
    ENSRNOP00000067850.3, ENSRNOT00000074653.4
    Conserved Domains (3) summary
    cd00161
    Location:2820 → 2949
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00030
    Location:2556 → 2637
    Crystall; Beta/Gamma crystallin
    pfam00652
    Location:2821 → 2947
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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