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Asmtl acetylserotonin O-methyltransferase-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 288527, updated on 2-Nov-2024

Summary

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Official Symbol
Asmtlprovided by RGD
Official Full Name
acetylserotonin O-methyltransferase-likeprovided by RGD
Primary source
RGD:1306877
See related
EnsemblRapid:ENSRNOG00000028166 AllianceGenome:RGD:1306877
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable nucleoside triphosphate diphosphatase activity. Predicted to be located in cytosol. Orthologous to human ASMTL (acetylserotonin O-methyltransferase like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 111.7), Heart (RPKM 88.3) and 9 other tissues See more
Orthologs
human all
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Genomic context

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See Asmtl in Genome Data Viewer
Location:
12q11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (21429119..21431847)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (16315335..16318083)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (18532090..18534761)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene acetylserotonin O-methyltransferase Neighboring gene A-kinase anchoring protein 17A Neighboring gene interleukin 3 receptor subunit alpha Neighboring gene pumilio RNA-binding family member 3, pseudogene 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleoside triphosphate diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
N-acetylserotonin O-methyltransferase-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105915.2 → NP_001099385.2  N-acetylserotonin O-methyltransferase-like protein

    Status: VALIDATED

    Source sequence(s)
    BP484213, FM052956, FM053536, FM067394
    UniProtKB/TrEMBL
    A0A8I5ZM76, D4AA35
    Related
    ENSRNOP00000038215.5, ENSRNOT00000036606.8
    Conserved Domains (1) summary
    cd00555
    Location:15 → 209
    Maf; Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    21429119..21431847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089199.2 → XP_038945127.1  N-acetylserotonin O-methyltransferase-like protein isoform X2

    Conserved Domains (1) summary
    cl00276
    Location:15 → 129
    Maf_Ham1; Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, ...

  2. XM_006249001.4 → XP_006249063.1  N-acetylserotonin O-methyltransferase-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZM76, A0A8I6AKB0
    Related
    ENSRNOP00000095718.1, ENSRNOT00000108870.2
    Conserved Domains (1) summary
    cd00555
    Location:15 → 246
    Maf; Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or ...

  3. XM_039089200.2 → XP_038945128.1  N-acetylserotonin O-methyltransferase-like protein isoform X3

    UniProtKB/TrEMBL
    A6K208
    Conserved Domains (1) summary
    cl00276
    Location:1 → 117
    Maf_Ham1; Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, ...

  4. XM_039089202.2 → XP_038945130.1  N-acetylserotonin O-methyltransferase-like protein isoform X3

    UniProtKB/TrEMBL
    A6K208
    Conserved Domains (1) summary
    cl00276
    Location:1 → 117
    Maf_Ham1; Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, ...

  5. XM_039089203.2 → XP_038945131.1  N-acetylserotonin O-methyltransferase-like protein isoform X3

    UniProtKB/TrEMBL
    A6K208
    Conserved Domains (1) summary
    cl00276
    Location:1 → 117
    Maf_Ham1; Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, ...

  6. XM_039089201.2 → XP_038945129.1  N-acetylserotonin O-methyltransferase-like protein isoform X3

    UniProtKB/TrEMBL
    A6K208
    Conserved Domains (1) summary
    cl00276
    Location:1 → 117
    Maf_Ham1; Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, ...

RNA

  1. XR_010056370.1 RNA Sequence

  2. XR_005491610.2 RNA Sequence

  3. XR_005491611.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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