Kif28p kinesin family member 28, pseudogene [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Kif28pprovided by RGD
Official Full Name: kinesin family member 28, pseudogeneprovided by RGD
Primary source: RGD:1559696
See related: EnsemblRapid:ENSRNOG00000050602 AllianceGenome:RGD:1559696
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: KLP6; RGD1559696
Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in mitochondrion organization and organelle transport along microtubule. Located in mitochondrial membrane. Orthologous to human KIF28P (kinesin family member 28, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Liver (RPKM 2.0), Kidney (RPKM 1.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q26

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (93959492..94014255, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (91427527..91482297, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (97969335..98023829, complement)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule motor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mitochondrion organization	IDA Inferred from Direct Assay more info	PubMed
involved_in organelle transport along microtubule	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vesicle transport along microtubule	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of kinesin complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: kinesin-like protein KIF28P

Names: Kinesin-like protein 6; kinesin-like protein KLP6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001270385.2 → NP_001257314.1 kinesin-like protein KIF28P

See identical proteins and their annotated locations for NP_001257314.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000013

UniProtKB/Swiss-Prot

F8WLE0

Related

ENSRNOP00000064972.1, ENSRNOT00000075426.3

Conserved Domains (3) summary

cd00060
Location:440 → 537

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

pfam12423
Location:655 → 693

KIF1B; Kinesin protein 1B

cl22853
Location:15 → 370

Motor_domain; Myosin and Kinesin motor domain