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Abcg3l1 ATP-binding cassette, subfamily G (WHITE), member 3-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 289453, updated on 5-Mar-2024

Summary

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Symbol
Abcg3l1provided by RGD
Full Name
ATP-binding cassette, subfamily G (WHITE), member 3-like 1provided by RGD
Primary source
RGD:1303294
See related
Ensembl:ENSRNOG00000069481 AllianceGenome:RGD:1303294
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Abcg3
Summary
Predicted to enable ABC-type transporter activity and ATP binding activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 59.7), Adrenal (RPKM 59.5) and 9 other tissues See more
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Genomic context

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See Abcg3l1 in Genome Data Viewer
Location:
14p22
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (5429242..5481948, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (5124541..5177265, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (6488655..6541220, complement)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 996 like 2 Neighboring gene zinc finger protein 951 like 1 Neighboring gene uncharacterized LOC134481818 Neighboring gene THO complex subunit 2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC114213

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables efflux transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables riboflavin transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in riboflavin transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
broad substrate specificity ATP-binding cassette transporter ABCG2
Names
ATP-binding cassette, sub-family G (WHITE), member 3
ATP-binding cassette, sub-family G (WHITE), member 3-like 1
NP_001004076.2
XP_017454584.1
XP_017454585.1
XP_038947589.1
XP_063128962.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004076.2 → NP_001004076.2  broad substrate specificity ATP-binding cassette transporter ABCG2

    See identical proteins and their annotated locations for NP_001004076.2

    Status: PROVISIONAL

    Source sequence(s)
    BC098896
    UniProtKB/TrEMBL
    Q4KM08, Q68HW7
    Related
    ENSRNOP00000046549.3, ENSRNOT00000042532.7
    Conserved Domains (3) summary
    TIGR00955
    Location:64 → 644
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:369 → 572
    ABC2_membrane; ABC-2 type transporter
    cl21455
    Location:35 → 261
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    5429242..5481948 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017599095.3 → XP_017454584.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1

    UniProtKB/TrEMBL
    Q4KM08, Q68HW7
    Conserved Domains (3) summary
    TIGR00955
    Location:64 → 644
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:369 → 572
    ABC2_membrane; ABC-2 type transporter
    cl21455
    Location:35 → 261
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_063272892.1 → XP_063128962.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X3

  3. XM_017599096.3 → XP_017454585.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2

    UniProtKB/TrEMBL
    Q68HW7

  4. XM_039091661.2 → XP_038947589.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X4

    Conserved Domains (2) summary
    pfam19055
    Location:237 → 293
    ABC2_membrane_7; ABC-2 type transporter
    cl38936
    Location:35 → 261
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_010057347.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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