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Pno1 partner of NOB1 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 289809, updated on 18-Sep-2024

Summary

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Official Symbol
Pno1provided by RGD
Official Full Name
partner of NOB1 homologprovided by RGD
Primary source
RGD:727882
See related
EnsemblRapid:ENSRNOG00000005524 AllianceGenome:RGD:727882
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable RNA binding activity. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human PNO1 (partner of NOB1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 118.2), Adrenal (RPKM 92.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Pno1 in Genome Data Viewer
Location:
14q22
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (95811335..95819903, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (91609711..91618280, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (100364192..100372760, complement)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096673 Neighboring gene cannabinoid receptor interacting protein 1 Neighboring gene protein phosphatase 3, regulatory subunit B, alpha Neighboring gene uncharacterized LOC134481791 Neighboring gene dynein axonemal assembly factor 10 Neighboring gene C1D nuclear receptor corepressor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of a novel human RNA binding protein gene PNO1. Zhou GJ, et al. DNA Seq, 2004 Jun. PMID 15497447
  2. CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation. Zemp I, et al. J Cell Sci, 2014 Mar 15. PMID 24424021
  3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
RNA-binding protein PNO1
Names
putatative 28 kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199083.2 → NP_954514.2  RNA-binding protein PNO1

    See identical proteins and their annotated locations for NP_954514.2

    Status: VALIDATED

    Source sequence(s)
    AI043694, AY344057
    UniProtKB/Swiss-Prot
    Q6VBQ8
    UniProtKB/TrEMBL
    A6JPZ1
    Related
    ENSRNOP00000088236.1, ENSRNOT00000110369.2
    Conserved Domains (2) summary
    smart00322
    Location:176 → 228
    KH; K homology RNA-binding domain
    COG1094
    Location:71 → 246
    Krr1; rRNA processing protein Krr1/Pno1, contains KH domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    95811335..95819903 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6VBQ8.1 GenPept UniProtKB/Swiss-Prot:Q6VBQ8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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