U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cep44 centrosomal protein 44 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290722, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Cep44provided by RGD
Official Full Name
centrosomal protein 44provided by RGD
Primary source
RGD:1308517
See related
EnsemblRapid:ENSRNOG00000010566 AllianceGenome:RGD:1308517
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308517
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in centriole replication and centriole-centriole cohesion. Predicted to be located in centriole. Predicted to be active in centrosome and spindle pole. Orthologous to human CEP44 (centrosomal protein 44). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Adrenal (RPKM 45.4), Thymus (RPKM 43.9) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Cep44 in Genome Data Viewer
Location:
16p11
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (38722259..38741603)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (33711548..33733226)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (37177379..37199043)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene F-box protein 8 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene ribosomal oxygenase 2, pseudogene 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
  2. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC125247

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
enables microtubule binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in centriole replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in centriole replication ISO
Inferred from Sequence Orthology
more info
  
involved_in centriole replication ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in centriole-centriole cohesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in centriole-centriole cohesion ISO
Inferred from Sequence Orthology
more info
  
involved_in centriole-centriole cohesion ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in centrosome cycle ISO
Inferred from Sequence Orthology
more info
  
involved_in centrosome cycle ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
located_in centriole ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in midbody IEA
Inferred from Electronic Annotation
more info
  
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
  
located_in spindle pole ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
centrosomal protein of 44 kDa

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037181.1 → NP_001032258.1  centrosomal protein of 44 kDa

    See identical proteins and their annotated locations for NP_001032258.1

    Status: PROVISIONAL

    Source sequence(s)
    BC107470
    UniProtKB/Swiss-Prot
    Q3B7T8
    UniProtKB/TrEMBL
    A6KIX5
    Related
    ENSRNOP00000083699.2, ENSRNOT00000100488.2
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    38722259..38741603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253089.4 → XP_006253151.1  centrosomal protein of 44 kDa isoform X3

    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  2. XM_006253090.5 → XP_006253152.1  centrosomal protein of 44 kDa isoform X6

    Conserved Domains (1) summary
    pfam15007
    Location:5 → 79
    CEP44; Centrosomal spindle body, CEP44

  3. XM_039094372.2 → XP_038950300.1  centrosomal protein of 44 kDa isoform X7

    UniProtKB/TrEMBL
    A6KIX6
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  4. XM_063275226.1 → XP_063131296.1  centrosomal protein of 44 kDa isoform X4

  5. XM_006253087.5 → XP_006253149.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006253149.1

    UniProtKB/Swiss-Prot
    Q3B7T8
    UniProtKB/TrEMBL
    A6KIX5
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  6. XM_063275225.1 → XP_063131295.1  centrosomal protein of 44 kDa isoform X3

  7. XM_063275228.1 → XP_063131298.1  centrosomal protein of 44 kDa isoform X6

  8. XM_008771223.3 → XP_008769445.1  centrosomal protein of 44 kDa isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZZU2
    Related
    ENSRNOP00000014083.6, ENSRNOT00000014083.7
    Conserved Domains (1) summary
    pfam15007
    Location:14 → 111
    CEP44; Centrosomal spindle body, CEP44

  9. XM_063275227.1 → XP_063131297.1  centrosomal protein of 44 kDa isoform X5

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3B7T8.1 GenPept UniProtKB/Swiss-Prot:Q3B7T8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools