Ubxn8 UBX domain protein 8 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ubxn8provided by RGD
Official Full Name: UBX domain protein 8provided by RGD
Primary source: RGD:1306023
See related: EnsemblRapid:ENSRNOG00000091028 AllianceGenome:RGD:1306023
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ubxd6; RGD1306023
Summary: Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum; nucleolus; and nucleoplasm. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human UBXN8 (UBX domain protein 8). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 87.8), Kidney (RPKM 64.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 16q12.3

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	16	NC_086034.1 (65239149..65260743)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	16	NC_051351.1 (58536086..58557684)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	16	NC_005115.4 (62251243..62272838)

Chromosome 16 - NC_086034.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ubiquitin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in ERAD pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: UBX domain-containing protein 8

Names: UBX domain containing 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106086.1 → NP_001099556.1 UBX domain-containing protein 8

See identical proteins and their annotated locations for NP_001099556.1

Status: PROVISIONAL

Source sequence(s)

CH473970

UniProtKB/TrEMBL

A6IVT0, D3ZUE3

Related

ENSRNOP00000111844.1, ENSRNOT00000165631.1

Conserved Domains (1) summary

cd01774
Location:195 → 270

UBX_UBXN8; Ubiquitin regulatory domain X (UBX) found in UBX domain protein 8 (UBXN8) and similar proteins