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Nrsn1 neurensin 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291129, updated on 10-Jul-2024

Summary

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Official Symbol
Nrsn1provided by RGD
Official Full Name
neurensin 1provided by RGD
Primary source
RGD:1307833
See related
EnsemblRapid:ENSRNOG00000017444 AllianceGenome:RGD:1307833
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Vmp
Summary
Predicted to be involved in nervous system development. Predicted to be located in cytoplasmic vesicle and growth cone. Predicted to be active in neuron projection; neuronal cell body; and transport vesicle. Orthologous to human NRSN1 (neurensin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 285.4) See more
Orthologs
human mouse all
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Genomic context

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See Nrsn1 in Genome Data Viewer
Location:
17p11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (40234302..40252614)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (39806238..39824550)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (41798767..41816346)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon AGG) 58 Neighboring gene triosephosphate isomerase 1, pseudogene 2 Neighboring gene uncharacterized LOC134482709 Neighboring gene doublecortin domain containing 2 Neighboring gene ribosomal protein L32, pseudogene 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Developmentally regulated expression of Neuro-p24 and its possible function in neurite extension. Araki M, et al. Neurosci Res, 2002 Dec. PMID 12445626
  2. A newly identified membrane protein localized exclusively in intracellular organelles of neurons. Kadota Y, et al. Brain Res Mol Brain Res, 1997 Jun. PMID 9191101
  3. Molecular characterization of a transport vesicle protein Neurensin-2, a homologue of Neurensin-1, expressed in neural cells. Nakanishi K, et al. Brain Res, 2006 Apr 7. PMID 16527258
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nervous system development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
  
located_in growth cone ISO
Inferred from Sequence Orthology
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
  
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
  
is_active_in transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
neurensin-1
Names
vesicular membrane protein p24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106109.2 → NP_001099579.2  neurensin-1

    See identical proteins and their annotated locations for NP_001099579.2

    Status: PROVISIONAL

    Source sequence(s)
    BC166919
    UniProtKB/TrEMBL
    B2RYS1
    Related
    ENSRNOP00000023519.3, ENSRNOT00000023519.7
    Conserved Domains (1) summary
    pfam14927
    Location:24 → 154
    Neurensin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    40234302..40252614
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039095508.2 → XP_038951436.1  neurensin-1 isoform X1

    UniProtKB/TrEMBL
    A6KLD9, G3V892
    Conserved Domains (1) summary
    pfam14927
    Location:24 → 154
    Neurensin
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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