U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp236 zinc finger protein 236 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291409, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp236provided by RGD
Official Full Name
zinc finger protein 236provided by RGD
Primary source
RGD:1309670
See related
EnsemblRapid:ENSRNOG00000016303 AllianceGenome:RGD:1309670
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cellular response to glucose stimulus and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF236 (zinc finger protein 236). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 96.1), Spleen (RPKM 68.1) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zfp236 in Genome Data Viewer
Location:
18q12.3
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (78251248..78351037, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (75976478..76072428, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (79447384..79543271, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene galanin receptor 1 Neighboring gene myelin basic protein Neighboring gene uncharacterized LOC108348833 Neighboring gene uncharacterized LOC120098255 Neighboring gene ribosomal protein L9, pseudogene 18

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of glucose-regulated genes in human mesangial cells by mRNA differential display. Holmes DI, et al. Biochem Biophys Res Commun, 1997 Sep 8. PMID 9299475
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cellular response to glucose stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 236

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427206.1 → NP_001414135.1  zinc finger protein 236

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    A0A8I6AC96
    Related
    ENSRNOP00000089231.1, ENSRNOT00000111597.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    78251248..78351037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255013.4 → XP_006255075.1  zinc finger protein 236 isoform X3

    UniProtKB/TrEMBL
    A0A8I6A431
    Related
    ENSRNOP00000101311.1, ENSRNOT00000134404.1
    Conserved Domains (5) summary
    COG5048
    Location:197 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:201 → 221
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1257 → 1277
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:199 → 221
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:1185 → 1209
    zf-H2C2_2; Zinc-finger double domain

  2. XM_008772218.4 → XP_008770440.1  zinc finger protein 236 isoform X1

    See identical proteins and their annotated locations for XP_008770440.1

    UniProtKB/TrEMBL
    A0A8I5ZXK0, A0A8I6A431
    Related
    ENSRNOP00000084581.1, ENSRNOT00000114662.2
    Conserved Domains (6) summary
    COG5048
    Location:181 → 534
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:185 → 205
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1241 → 1261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:183 → 205
    zf-C2H2; Zinc finger, C2H2 type
    pfam04005
    Location:1347 → 1581
    Hus1; Hus1-like protein
    pfam13465
    Location:1169 → 1193
    zf-H2C2_2; Zinc-finger double domain

  3. XM_063277157.1 → XP_063133227.1  zinc finger protein 236 isoform X2

    Related
    ENSRNOP00000022086.9, ENSRNOT00000022086.9

  4. XM_039097350.2 → XP_038953278.1  zinc finger protein 236 isoform X5

    UniProtKB/TrEMBL
    A0A8I6A431, F1LXC0
    Conserved Domains (6) summary
    COG5048
    Location:78 → 431
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:82 → 102
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1138 → 1158
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05109
    Location:1256 → 1451
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13465
    Location:1066 → 1090
    zf-H2C2_2; Zinc-finger double domain
    cd20908
    Location:1544 → 1592
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

  5. XM_039097349.2 → XP_038953277.1  zinc finger protein 236 isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZJ55, A0A8I6A431
    Related
    ENSRNOP00000076412.1, ENSRNOT00000103278.2
    Conserved Domains (6) summary
    COG5048
    Location:97 → 450
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:101 → 121
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1157 → 1177
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05109
    Location:1275 → 1470
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13465
    Location:1085 → 1109
    zf-H2C2_2; Zinc-finger double domain
    cd20908
    Location:1563 → 1611
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

  6. XM_039097351.2 → XP_038953279.1  zinc finger protein 236 isoform X7

    Conserved Domains (7) summary
    COG5048
    Location:213 → 618
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:732 → 752
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:816 → 836
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05109
    Location:934 → 1129
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00096
    Location:43 → 65
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:744 → 768
    zf-H2C2_2; Zinc-finger double domain
    cd20908
    Location:1222 → 1270
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

  7. XM_006255016.5 → XP_006255078.1  zinc finger protein 236 isoform X6

    UniProtKB/TrEMBL
    A0A8I6A431
    Conserved Domains (5) summary
    COG5048
    Location:197 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:201 → 221
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1257 → 1277
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:199 → 221
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:1185 → 1209
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. XR_361554.4 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001191696.1: Suppressed sequence

    Description
    NM_001191696.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials