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Prrc1 proline-rich coiled-coil 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291444, updated on 18-Sep-2024

Summary

Official Symbol
Prrc1provided by RGD
Official Full Name
proline-rich coiled-coil 1provided by RGD
Primary source
RGD:1565632
See related
EnsemblRapid:ENSRNOG00000016433 AllianceGenome:RGD:1565632
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Prcc1
Summary
Predicted to enable identical protein binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in activation of protein kinase A activity. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. Orthologous to human PRRC1 (proline rich coiled-coil 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 93.6), Lung (RPKM 92.4) and 9 other tissues See more
Orthologs
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Genomic context

See Prrc1 in Genome Data Viewer
Location:
18q12.1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (53010606..53047601)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (50812548..50846273)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (52423845..52460854)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 4, regulatory subunit 1, pseudogene 1 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene uncharacterized LOC100910150 Neighboring gene uncharacterized LOC100910189 Neighboring gene cortexin 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC124825

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein kinase A regulatory subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in epithelial structure maintenance IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
protein PRRC1
Names
proline-rich and coiled-coil-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033887.2NP_001029059.2  protein PRRC1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/Swiss-Prot
    A0A8I6G4Z0, Q3T1I4
    UniProtKB/TrEMBL
    A6IX75, G3V834
    Related
    ENSRNOP00000022021.6, ENSRNOT00000022017.8
    Conserved Domains (1) summary
    cl00866
    Location:261374
    NTPase_I-T; Protein of unknown function DUF84

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    53010606..53047601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096645.2XP_038952573.1  protein PRRC1 isoform X2

    UniProtKB/TrEMBL
    G3V834
    Conserved Domains (2) summary
    PHA03247
    Location:50197
    PHA03247; large tegument protein UL36; Provisional
    cl00866
    Location:261381
    NTPase_I-T; Protein of unknown function DUF84
  2. XM_006254746.4XP_006254808.1  protein PRRC1 isoform X1

    See identical proteins and their annotated locations for XP_006254808.1

    UniProtKB/Swiss-Prot
    A0A8I6G4Z0, Q3T1I4
    UniProtKB/TrEMBL
    A6IX75, G3V834
    Conserved Domains (1) summary
    cl00866
    Location:261374
    NTPase_I-T; Protein of unknown function DUF84