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Cfdp1 craniofacial development protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 292027, updated on 4-Apr-2024

Summary

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Official Symbol
Cfdp1provided by RGD
Official Full Name
craniofacial development protein 1provided by RGD
Primary source
RGD:735080
See related
Ensembl:ENSRNOG00000019326 AllianceGenome:RGD:735080
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to act upstream of or within several processes, including cell adhesion; negative regulation of fibroblast apoptotic process; and regulation of cell shape. Predicted to be located in kinetochore. Orthologous to human CFDP1 (craniofacial development protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 209.3), Adrenal (RPKM 179.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Cfdp1 in Genome Data Viewer
Location:
19q12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (56627596..56733099, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (39718313..39823824, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (43989596..44078320, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene chymotrypsinogen B1 Neighboring gene BCAR1 scaffold protein, Cas family member Neighboring gene uncharacterized LOC134483372 Neighboring gene transmembrane protein 170A Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex. Iwashita S, et al. Biosci Rep, 2020 Jun 26. PMID 32432658, Free PMC Article
  2. CP27 affects viability, proliferation, attachment and gene expression in embryonic fibroblasts. Luan X, et al. Cell Prolif, 2002 Aug. PMID 12153613, Free PMC Article
  3. Cloning, gene expression, and characterization of CP27, a novel gene in mouse embryogenesis. Diekwisch TG, et al. Gene, 1999 Jul 22. PMID 10415329
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex.
    Title: Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell adhesion ISO
Inferred from Sequence Orthology
more info
  
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fibroblast apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of fibroblast apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of fibroblast apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of fibroblast apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of cell shape ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
craniofacial development protein 1
Names
bucentaur

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199378.5 → NP_955410.1  craniofacial development protein 1

    See identical proteins and their annotated locations for NP_955410.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/Swiss-Prot
    Q75UQ2
    UniProtKB/TrEMBL
    A0A8L2QE45, A6IZB0
    Related
    ENSRNOP00000083789.1, ENSRNOT00000112483.1
    Conserved Domains (1) summary
    pfam07572
    Location:218 → 291
    BCNT; Bucentaur or craniofacial development

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    56627596..56733099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039097633.2 → XP_038953561.1  craniofacial development protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K6H5, A0A8L2QE45
    Related
    ENSRNOP00000073816.1
    Conserved Domains (1) summary
    pfam07572
    Location:221 → 266
    BCNT; Bucentaur or craniofacial development
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q75UQ2.1 GenPept UniProtKB/Swiss-Prot:Q75UQ2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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