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Aig1 androgen-induced 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 292486, updated on 2-Nov-2024

Summary

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Official Symbol
Aig1provided by RGD
Official Full Name
androgen-induced 1provided by RGD
Primary source
RGD:1562920
See related
EnsemblRapid:ENSRNOG00000010753 AllianceGenome:RGD:1562920
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562920
Summary
Predicted to enable hydrolase activity. Predicted to be involved in long-chain fatty acid catabolic process. Predicted to be located in membrane. Predicted to be active in endomembrane system. Orthologous to human AIG1 (androgen induced 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 41.7), Adrenal (RPKM 34.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Aig1 in Genome Data Viewer
Location:
1p13
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (9866546..10089454, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (8046430..8269276, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (7816841..8038805, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098785 Neighboring gene cofilin 1, pseudogene 8 Neighboring gene uncharacterized LOC134484948 Neighboring gene HIVEP zinc finger 2 Neighboring gene ribosomal protein L13A, pseudogene 9 Neighboring gene transfer RNA alanine (anticodon AGC) 27

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Parsons WH, et al. Nat Chem Biol, 2016 May. PMID 27018888, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables hydrolase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in long-chain fatty acid catabolic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
androgen-induced gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134425.1 → NP_001127897.1  androgen-induced gene 1 protein

    See identical proteins and their annotated locations for NP_001127897.1

    Status: PROVISIONAL

    Source sequence(s)
    BC167098
    UniProtKB/TrEMBL
    A6JP64, B2RZC0
    Related
    ENSRNOP00000039627.3, ENSRNOT00000046539.7
    Conserved Domains (1) summary
    pfam04750
    Location:12 → 219
    Far-17a_AIG1; FAR-17a/AIG1-like protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    9866546..10089454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039103611.2 → XP_038959539.1  androgen-induced gene 1 protein isoform X4

    Conserved Domains (1) summary
    pfam04750
    Location:12 → 185
    Far-17a_AIG1; FAR-17a/AIG1-like protein

  2. XM_039103617.2 → XP_038959545.1  androgen-induced gene 1 protein isoform X5

    UniProtKB/TrEMBL
    A0A8I5ZRM1, A0A8I5ZTN0
    Conserved Domains (1) summary
    pfam04750
    Location:12 → 133
    Far-17a_AIG1; FAR-17a/AIG1-like protein

  3. XM_039103609.2 → XP_038959537.1  androgen-induced gene 1 protein isoform X2

    UniProtKB/TrEMBL
    A6JP64
    Conserved Domains (1) summary
    pfam04750
    Location:12 → 185
    Far-17a_AIG1; FAR-17a/AIG1-like protein

  4. XM_039103610.2 → XP_038959538.1  androgen-induced gene 1 protein isoform X3

    Conserved Domains (1) summary
    pfam04750
    Location:12 → 133
    Far-17a_AIG1; FAR-17a/AIG1-like protein

  5. XM_006227642.5 → XP_006227704.1  androgen-induced gene 1 protein isoform X1

    UniProtKB/TrEMBL
    A0A8I6ABV0, A6JP64
    Related
    ENSRNOP00000091332.1, ENSRNOT00000114127.2
    Conserved Domains (1) summary
    pfam04750
    Location:12 → 219
    Far-17a_AIG1; FAR-17a/AIG1-like protein

  6. XM_039103626.2 → XP_038959554.1  androgen-induced gene 1 protein isoform X7

  7. XM_008758604.4 → XP_008756826.1  androgen-induced gene 1 protein isoform X9

    Conserved Domains (1) summary
    pfam04750
    Location:12 → 133
    Far-17a_AIG1; FAR-17a/AIG1-like protein

  8. XM_039103624.2 → XP_038959552.1  androgen-induced gene 1 protein isoform X6

    Conserved Domains (1) summary
    pfam04750
    Location:12 → 133
    Far-17a_AIG1; FAR-17a/AIG1-like protein

  9. XM_039103631.2 → XP_038959559.1  androgen-induced gene 1 protein isoform X8

    Conserved Domains (1) summary
    pfam04750
    Location:12 → 133
    Far-17a_AIG1; FAR-17a/AIG1-like protein

RNA

  1. XR_005500901.2 RNA Sequence

  2. XR_010064540.1 RNA Sequence

  3. XR_010064541.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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