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Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking [ Rattus norvegicus (Norway rat) ]

Gene ID: 292696, updated on 2-Nov-2024

Summary

Official Symbol
Clptm1provided by RGD
Official Full Name
CLPTM1 regulator of GABA type A receptor forward traffickingprovided by RGD
Primary source
RGD:1310959
See related
EnsemblRapid:ENSRNOG00000018255 AllianceGenome:RGD:1310959
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable GABA receptor binding activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Is active in GABA-ergic synapse. Orthologous to human CLPTM1 (CLPTM1 regulator of GABA type A receptor forward trafficking). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 498.2), Adrenal (RPKM 407.3) and 9 other tissues See more
Orthologs
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Genomic context

See Clptm1 in Genome Data Viewer
Location:
1q21
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88417447..88449047, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79289478..79321079, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80549051..80580665, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene CLK4-associating serine/arginine rich protein Neighboring gene RELB proto-oncogene, NF-kB subunit Neighboring gene uncharacterized LOC134482894 Neighboring gene apolipoprotein C2 Neighboring gene apolipoprotein C4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
putative lipid scramblase CLPTM1
Names
CLPTM1, transmembrane protein
cleft lip and palate associated transmembrane protein 1
cleft lip and palate transmembrane protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106232.1NP_001099702.1  putative lipid scramblase CLPTM1

    See identical proteins and their annotated locations for NP_001099702.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/TrEMBL
    A6J8Q9, B2RYF6, F7E127
    Related
    ENSRNOP00000024779.4, ENSRNOT00000024779.8
    Conserved Domains (1) summary
    pfam05602
    Location:60496
    CLPTM1; Cleft lip and palate transmembrane protein 1 (CLPTM1)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    88417447..88449047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)