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Irgq immunity-related GTPase Q [ Rattus norvegicus (Norway rat) ]

Gene ID: 292708, updated on 17-Aug-2024

Summary

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Official Symbol
Irgqprovided by RGD
Official Full Name
immunity-related GTPase Qprovided by RGD
Primary source
RGD:1309409
See related
EnsemblRapid:ENSRNOG00000070901 AllianceGenome:RGD:1309409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309409
Summary
Predicted to enable GTP binding activity. Orthologous to human IRGQ (immunity related GTPase Q). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 91.9), Kidney (RPKM 59.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Irgq in Genome Data Viewer
Location:
1q21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (89251846..89259799)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (80123925..80131881)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (81395922..81403872)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cell adhesion molecule 4 Neighboring gene zinc finger protein 428 Neighboring gene serine/arginine repetitive matrix 5 Neighboring gene phospholipase A2 inhibitor and Ly6/Plaur domain containing Neighboring gene X-ray repair cross complementing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
immunity-related GTPase family Q protein
Names
immunity-related GTPase family, Q

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135742.4 → NP_001129214.3  immunity-related GTPase family Q protein

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I5ZUT2
    Related
    ENSRNOP00000082584.1, ENSRNOT00000119508.2
    Conserved Domains (2) summary
    cd00267
    Location:3 → 62
    ABC_ATPase; ATP-binding cassette transporter nucleotide-binding domain
    cl38936
    Location:224 → 286
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    89251846..89259799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228410.5 → XP_006228472.2  immunity-related GTPase family Q protein isoform X1

    Conserved Domains (2) summary
    cd00267
    Location:13 → 72
    ABC_ATPase; ATP-binding cassette transporter nucleotide-binding domain
    pfam05049
    Location:204 → 296
    IIGP; Interferon-inducible GTPase (IIGP)
Nucleotide Protein Strain
Heading Accession and Version

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