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Mrps12 mitochondrial ribosomal protein S12 [ Rattus norvegicus (Norway rat) ]

Gene ID: 292758, updated on 10-Jul-2024

Summary

Official Symbol
Mrps12provided by RGD
Official Full Name
mitochondrial ribosomal protein S12provided by RGD
Primary source
RGD:1306221
See related
EnsemblRapid:ENSRNOG00000019949 AllianceGenome:RGD:1306221
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial small ribosomal subunit. Predicted to be active in ribosome. Orthologous to human MRPS12 (mitochondrial ribosomal protein S12). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 149.5), Heart (RPKM 139.4) and 9 other tissues See more
Orthologs
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Genomic context

See Mrps12 in Genome Data Viewer
Location:
1q21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (93153424..93156422, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (84025896..84028896, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (86920679..86923626, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene MARCKS-related protein-like Neighboring gene uncharacterized LOC134485106 Neighboring gene F-box protein 27 Neighboring gene F-box protein 17 Neighboring gene seryl-tRNA synthetase 2, mitochondrial Neighboring gene NFKB inhibitor beta Neighboring gene coiled-coil glutamate-rich protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
small ribosomal subunit protein uS12m
Names
28S ribosomal protein S12, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106239.1NP_001099709.1  small ribosomal subunit protein uS12m

    See identical proteins and their annotated locations for NP_001099709.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/TrEMBL
    A6J9K4, D3ZQX3
    Related
    ENSRNOP00000027029.3, ENSRNOT00000027029.6
    Conserved Domains (1) summary
    cd03368
    Location:32138
    Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    93153424..93156422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228652.5XP_006228714.1  small ribosomal subunit protein uS12m isoform X1

    See identical proteins and their annotated locations for XP_006228714.1

    UniProtKB/TrEMBL
    A6J9K4, D3ZQX3
    Conserved Domains (1) summary
    cd03368
    Location:32138
    Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...
  2. XM_006228651.3XP_006228713.1  small ribosomal subunit protein uS12m isoform X1

    See identical proteins and their annotated locations for XP_006228713.1

    UniProtKB/TrEMBL
    A6J9K4, D3ZQX3
    Conserved Domains (1) summary
    cd03368
    Location:32138
    Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...