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Rpl29 ribosomal protein L29 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29283, updated on 10-Jul-2024

Summary

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Official Symbol
Rpl29provided by RGD
Official Full Name
ribosomal protein L29provided by RGD
Primary source
RGD:62069
See related
EnsemblRapid:ENSRNOG00000011138 AllianceGenome:RGD:62069
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable heparin binding activity. Predicted to be a structural constituent of ribosome. Involved in aging. Located in ribosome. Part of cytosolic large ribosomal subunit. Orthologous to human RPL29 (ribosomal protein L29). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 456.0), Spleen (RPKM 379.2) and 9 other tissues See more
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Genomic context

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See Rpl29 in Genome Data Viewer
Location:
8q32
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (115056443..115949677)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (107068929..107070963)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (115131228..115133401)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2, pseudogene 1 Neighboring gene ATPase secretory pathway Ca2+ transporting 1 Neighboring gene asteroid homolog 1 Neighboring gene ribosomal protein L29, pseudogene 14 Neighboring gene 5S ribosomal RNA Neighboring gene phosphoinositide-3-kinase, regulatory subunit 4 Neighboring gene collagen type VI alpha 6 chain Neighboring gene uncharacterized LOC103693167 Neighboring gene transfer RNA leucine (anticodon AAG) 7 Neighboring gene collagen type VI alpha 5 chain Neighboring gene collagen, type VI, alpha 4 Neighboring gene ribosomal protein L6, pseudogene 10 Neighboring gene microRNA let-7g Neighboring gene glycerate kinase Neighboring gene WD repeat domain 82 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1M Neighboring gene uncharacterized LOC120094254 Neighboring gene twinfilin actin-binding protein 2 Neighboring gene 5'-aminolevulinate synthase 1 Neighboring gene toll-like receptor 9 Neighboring gene POC1 centriolar protein A Neighboring gene uncharacterized LOC134480228 Neighboring gene dual specificity phosphatase 7 Neighboring gene abhydrolase domain containing 14A Neighboring gene aminoacylase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The primary structure of rat ribosomal protein L29. Chan YL, et al. Biochem Biophys Res Commun, 1993 Apr 30. PMID 8484767
  2. Purification, primary structure and molecular cloning of a rat ribosomal protein showing homology with yeast ribosomal protein YL34. Svoboda M, et al. Eur J Biochem, 1992 Feb 1. PMID 1735422
  3. p23, a novel mammalian nucleic acid-binding protein with homology to the yeast ribosomal protein YL43. Ostvold AC, et al. FEBS Lett, 1992 Feb 24. PMID 1544448
  4. Gene expression profiling suggests a pathological role of human bone marrow-derived mesenchymal stem cells in aging-related skeletal diseases. Jiang SS, et al. Aging (Albany NY), 2011 Jul. PMID 21808097, Free PMC Article
  5. Global growth deficiencies in mice lacking the ribosomal protein HIP/RPL29. Kirn-Safran CB, et al. Dev Dyn, 2007 Feb. PMID 17195189

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables heparin binding ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell-substrate adhesion ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within fibroblast proliferation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within multicellular organism growth ISO
Inferred from Sequence Orthology
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasmic side of rough endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  
located_in ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein eL29
Names
60S ribosomal protein L29
P23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017150.1 → NP_058846.1  large ribosomal subunit protein eL29

    See identical proteins and their annotated locations for NP_058846.1

    Status: PROVISIONAL

    Source sequence(s)
    X68283
    UniProtKB/Swiss-Prot
    P25886
    UniProtKB/TrEMBL
    A6I2R0, M0R6U8
    Conserved Domains (1) summary
    pfam01779
    Location:4 → 42
    Ribosomal_L29e; Ribosomal L29e protein family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    115056443..115949677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063265012.1 → XP_063121082.1  large ribosomal subunit protein eL29 isoform X1

    UniProtKB/Swiss-Prot
    P25886
    UniProtKB/TrEMBL
    A6I2R0, M0R6U8

  2. XM_063265014.1 → XP_063121084.1  large ribosomal subunit protein eL29 isoform X1

    UniProtKB/Swiss-Prot
    P25886
    UniProtKB/TrEMBL
    A6I2R0, M0R6U8

  3. XM_063265010.1 → XP_063121080.1  large ribosomal subunit protein eL29 isoform X1

    UniProtKB/Swiss-Prot
    P25886
    UniProtKB/TrEMBL
    A6I2R0, M0R6U8

  4. XM_063265011.1 → XP_063121081.1  large ribosomal subunit protein eL29 isoform X1

    UniProtKB/Swiss-Prot
    P25886
    UniProtKB/TrEMBL
    A6I2R0, M0R6U8
    Related
    ENSRNOP00000100353.1, ENSRNOT00000158949.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25886.3 GenPept UniProtKB/Swiss-Prot:P25886

Gene LinkOut

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