U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tm2d3 TM2 domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 292995, updated on 2-Nov-2024

Summary

Official Symbol
Tm2d3provided by RGD
Official Full Name
TM2 domain containing 3provided by RGD
Primary source
RGD:1564929
See related
EnsemblRapid:ENSRNOG00000011290 AllianceGenome:RGD:1564929
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564929
Summary
Predicted to be involved in lateral inhibition. Predicted to be located in membrane. Orthologous to human TM2D3 (TM2 domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 59.5), Heart (RPKM 50.6) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tm2d3 in Genome Data Viewer
Location:
1q22
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (128677680..128687580)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (119267194..119277094)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (126573474..126595778)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099841 Neighboring gene threonyl-tRNA synthetase 3 Neighboring gene uncharacterized LOC108349586 Neighboring gene uncharacterized LOC120099842 Neighboring gene CWC15 spliceosome-associated protein, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
TM2 domain-containing protein 3

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106267.2NP_001099737.1  TM2 domain-containing protein 3 isoform 1

    See identical proteins and their annotated locations for NP_001099737.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I6ACD9, A6JBN3
    Related
    ENSRNOP00000091784.1, ENSRNOT00000094329.2
    Conserved Domains (1) summary
    pfam05154
    Location:196245
    TM2; TM2 domain
  2. NM_001419455.1NP_001406384.1  TM2 domain-containing protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
  3. NM_001419456.1NP_001406385.1  TM2 domain-containing protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
  4. NM_001419457.1NP_001406386.1  TM2 domain-containing protein 3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6JBN4, D3ZQU1
    Related
    ENSRNOP00000015287.8, ENSRNOT00000015287.9
  5. NM_001419458.1NP_001406387.1  TM2 domain-containing protein 3 isoform 5

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    128677680..128687580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)