Btbd1 BTB domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Btbd1provided by RGD
Official Full Name: BTB domain containing 1provided by RGD
Primary source: RGD:1310962
See related: EnsemblRapid:ENSRNOG00000019529 AllianceGenome:RGD:1310962
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable cullin family protein binding activity and identical protein binding activity. Predicted to be involved in neurogenesis. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in P-body and cytosol. Orthologous to human BTBD1 (BTB domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Heart (RPKM 868.9), Muscle (RPKM 814.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q31

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (145143806..145183653, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (135734549..135773067, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (143609729..143647124, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH132921 (e-PCR)
- UniSTS:216204

RH129884 (e-PCR)
- UniSTS:213172

AA874987 (e-PCR)
- UniSTS:245493

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables cullin family protein binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in neurogenesis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in P-body	IBA Inferred from Biological aspect of Ancestor more info
located_in P-body	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic ribonucleoprotein granule	ISO Inferred from Sequence Orthology more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: BTB/POZ domain-containing protein 1

Names: BTB (POZ) domain containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001011932.1 → NP_001011932.1 BTB/POZ domain-containing protein 1

See identical proteins and their annotated locations for NP_001011932.1

Status: PROVISIONAL

Source sequence(s)

BC085850

UniProtKB/TrEMBL

Q5RKI2

Related

ENSRNOP00000026595.4, ENSRNOT00000026595.7

Conserved Domains (4) summary

smart00225
Location:94 → 181

BTB; Broad-Complex, Tramtrack and Bric a brac

smart00875
Location:193 → 292

BACK; BTB And C-terminal Kelch

pfam00651
Location:68 → 177

BTB; BTB/POZ domain

pfam08005
Location:340 → 486

PHR; PHR domain